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Protein Overview: Gga-PB

General Information:
Name(s) found: Gga-PB / FBpp0071298 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Gga is referred to in FlyBase by the symbol Dmel\Gga (CG3002, FBgn0030141). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9495067..9498315. It has the cytological map location 8F1. There is experimental evidence that it has the molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: post-Golgi vesicle-mediated transport. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 660 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IC]
    Golgi apparatus part [IEA]
    clathrin adaptor complex [IEA]
    Biological Process: post-Golgi vesicle-mediated transport [ISS]
    intracellular protein transport [IEA]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDESIMEE MLERATNPAQ KIDELGVQMF CIVVKSNAQL VHKAQEMIVA KVRSTNVTEA  60
   61 TRAISLLEEC MTQCGDDFQD EASKFRFLNE LIRLVSKKYK GAETPHEVKQ RIMECLLLWT 120
  121 TEFPQRQKIR DAYDMLRKEG DIEHGTTEAA VAKRESVLGT IDEAMFAKLI KSNNPENFKR 180
  181 ANLLLQYRMA QEARRNDLLA QHRLVLCEVQ ETMQLLNQML DTYDPANQDV SETLHELYKS 240
  241 CKKHKPIFQH LPQLLDDSDA QLVADTLDAN CALLATMQRY KLLVPSPTRS TAAALTTSAP 300
  301 TVASSVKSTA SSTTATTSSN NAQLLNELLG DLLIDGSNKA ATTATTSLPN AAASGSNPLA 360
  361 DLSDIFSSAL AESEAKQQSQ PFQNATTLLE PQVISQGTTT EALANGNGGS ASKVPETIRK 420
  421 MPQIDMLSEE LFQQILPTQD RMPSFKRDPE KITLNDLARE RMHIKAPEEP TTANDPASDS 480
  481 APAIATATAT VDSIDDVPLL SDDVEKKDEA VVAPVTVVPP AKPLSEINVE LDNIQATGEQ 540
  541 RIVLDDDDMQ LSLNFTSDRP GHRVSVIVIS AQNKSRQPVR DFQFEASVKK PCKVRLLTPT 600
  601 DSQMPPHKPF RPATPINQVM LLLNPTGKAV DVTCIVGYKL GDDPDPIKES IVAKGIDYVD 660
  661

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 53.522879 Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide
    2 View Details [156..321] PSI-BLAST 13.522879 Crystal structure of Tom1 GAT domain in complex with ubiquitin
    3 View Details [322..437] deduced N/A No confident structure predictions are available.
    4 View Details [438..528] PSI-BLAST 3.69897 Sec24
    5 View Details [529..660] PSI-BLAST 18.30103 ADP-ribosylation factor binding protein Gga3 domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • clathrin binding
    		•  2.43251621028184 bayes_pls_golite062009
  • protein binding
    		•  2.16467447169895 bayes_pls_golite062009
  • binding
    		•  1.8321225578924 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.87586037360588 bayes_pls_golite062009
  • phospholipid binding
    		•  0.84481265656013 bayes_pls_golite062009
  • lipid binding
    		•  0.176990783274449 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • protein binding
    		•  1.57801165255065 bayes_pls_golite062009
  • binding
    		•  1.2747736774085 bayes_pls_golite062009
  • transporter activity
    		•  0.169557557237959 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle