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View Structure Prediction Details

Protein: Gga-PB
Organism: Drosophila melanogaster
Length: 660 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Gga-PB.

Description E-value Query
Range
Subject
Range
gi|197100544 - gi|197100544|ref|NP_001125813.1| golgi associated, gamma adaptin ear containing, ARF binding protein...
gi|55729281 - gi|55729281|emb|CAH91376.1| hypothetical protein [Pongo abelii]
357.0 [0..3] [660..4]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDESIMEE MLERATNPAQ KIDELGVQMF CIVVKSNAQL VHKAQEMIVA KVRSTNVTEA  60
   61 TRAISLLEEC MTQCGDDFQD EASKFRFLNE LIRLVSKKYK GAETPHEVKQ RIMECLLLWT 120
  121 TEFPQRQKIR DAYDMLRKEG DIEHGTTEAA VAKRE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1py1A
Description: Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 2.43251621028184 bayes_pls_golite062009
protein binding 2.16467447169895 bayes_pls_golite062009
binding 1.8321225578924 bayes_pls_golite062009
phosphoinositide binding 0.87586037360588 bayes_pls_golite062009
phospholipid binding 0.84481265656013 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [156-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVLGTIDEAM FAKLIKSNNP ENFKRANLLL QYRMAQEARR NDLLAQHRLV LCEVQETMQL  60
   61 LNQMLDTYDP ANQDVSETLH ELYKSCKKHK PIFQHLPQLL DDSDAQLVAD TLDANCALLA 120
  121 TMQRYKLLVP SPTRSTAAAL TTSAPTVASS VKSTASSTTA TTSSNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 1wrdA
Description: Crystal structure of Tom1 GAT domain in complex with ubiquitin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [322-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQLLNELLGD LLIDGSNKAA TTATTSLPNA AASGSNPLAD LSDIFSSALA ESEAKQQSQP  60
   61 FQNATTLLEP QVISQGTTTE ALANGNGGSA SKVPETIRKM PQIDMLSEEL FQQILP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [438-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQDRMPSFKR DPEKITLNDL ARERMHIKAP EEPTTANDPA SDSAPAIATA TATVDSIDDV  60
   61 PLLSDDVEKK DEAVVAPVTV VPPAKPLSEI N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [529-660]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VELDNIQATG EQRIVLDDDD MQLSLNFTSD RPGHRVSVIV ISAQNKSRQP VRDFQFEASV  60
   61 KKPCKVRLLT PTDSQMPPHK PFRPATPINQ VMLLLNPTGK AVDVTCIVGY KLGDDPDPIK 120
  121 ESIVAKGIDY VD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.30103
Match: 1p4uA
Description: ADP-ribosylation factor binding protein Gga3 domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.57801165255065 bayes_pls_golite062009
binding 1.2747736774085 bayes_pls_golite062009
transporter activity 0.169557557237959 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle