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View Structure Prediction Details

Protein: Gga-PB
Organism: Drosophila melanogaster
Length: 660 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Gga-PB.

Description E-value Query
Range
Subject
Range
gi|197100544 - gi|197100544|ref|NP_001125813.1| golgi associated, gamma adaptin ear containing, ARF binding protein...
gi|55729281 - gi|55729281|emb|CAH91376.1| hypothetical protein [Pongo abelii]
357.0 [0..3] [660..4]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDESIMEE MLERATNPAQ KIDELGVQMF CIVVKSNAQL VHKAQEMIVA KVRSTNVTEA  60
   61 TRAISLLEEC MTQCGDDFQD EASKFRFLNE LIRLVSKKYK GAETPHEVKQ RIMECLLLWT 120
  121 TEFPQRQKIR DAYDMLRKEG DIEHGTTEAA VAKRE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1py1A
Description: Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 2.43251621028184 bayes_pls_golite062009
protein binding 2.16467447169895 bayes_pls_golite062009
binding 1.8321225578924 bayes_pls_golite062009
phosphoinositide binding 0.87586037360588 bayes_pls_golite062009
phospholipid binding 0.84481265656013 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [156-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVLGTIDEAM FAKLIKSNNP ENFKRANLLL QYRMAQEARR NDLLAQHRLV LCEVQETMQL  60
   61 LNQMLDTYDP ANQDVSETLH ELYKSCKKHK PIFQHLPQLL DDSDAQLVAD TLDANCALLA 120
  121 TMQRYKLLVP SPTRSTAAAL TTSAPTVASS VKSTASSTTA TTSSNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 1wrdA
Description: Crystal structure of Tom1 GAT domain in complex with ubiquitin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [322-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQLLNELLGD LLIDGSNKAA TTATTSLPNA AASGSNPLAD LSDIFSSALA ESEAKQQSQP  60
   61 FQNATTLLEP QVISQGTTTE ALANGNGGSA SKVPETIRKM PQIDMLSEEL FQQILP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [438-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQDRMPSFKR DPEKITLNDL ARERMHIKAP EEPTTANDPA SDSAPAIATA TATVDSIDDV  60
   61 PLLSDDVEKK DEAVVAPVTV VPPAKPLSEI N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [529-660]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VELDNIQATG EQRIVLDDDD MQLSLNFTSD RPGHRVSVIV ISAQNKSRQP VRDFQFEASV  60
   61 KKPCKVRLLT PTDSQMPPHK PFRPATPINQ VMLLLNPTGK AVDVTCIVGY KLGDDPDPIK 120
  121 ESIVAKGIDY VD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.30103
Match: 1p4uA
Description: ADP-ribosylation factor binding protein Gga3 domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.57801165255065 bayes_pls_golite062009
binding 1.2747736774085 bayes_pls_golite062009
transporter activity 0.169557557237959 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle