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Protein Overview: CG4586-PA

General Information:
Name(s) found: CG4586-PA / FBpp0070963 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4586 (CG4586, FBgn0029924). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6863974..6866302. It has the cytological map location 6E4. Based on sequence similarity, it is predicted to have molecular function</span>: acyl-CoA oxidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; fatty acid beta-oxidation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 677 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [ISS]
    Biological Process: fatty acid beta-oxidation [IEA]
    oxidation reduction [IEA]
    Molecular Function: acyl-CoA dehydrogenase activity [IEA]
    acyl-CoA oxidase activity [ISS]
    FAD binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVNADLQRE RAAATLDSED FARWWAGGSG QLEERRALER RFYEDPDFAE PVHPSCLSYK  60
   61 ERYEQTVARS TRFLAKLRQW QREKQPQLQL SVNMLRDFRL LLSGSLGTGL FQQSFPLRVH 120
  121 FSMFMTTLLS QGTEEQQAQW LNRSWHMDGV LGTYAQTELG HGTFVRGLET RADYDPITQE 180
  181 FILNTPTQSS YKWWPGGLGN TANVAIVLAQ LYVKGKHYGL QSFVVRIRDE RTHEPLTGVD 240
  241 VGDIGPRLGG NGVNNGFLGL RDVRIPRNQM LMKNAQVLTD GTFVQGRPPL LLYGTMVYVR 300
  301 VITVKDVLFG LLQAATIATR YSVVRRQSRI NSDQPEVSVL DHITQQAKIL PQIARGVSYR 360
  361 LVSDWLWRFY EDVLRQLEDE STKGRNSLPE LHALSCCLKA VATDEASEGV DLLRKSCGGH 420
  421 GFLSSANFDS IYGLTAATYT YEGEYTVLLL QTARFLVRQY ADSLKRKVLP SSVSYLRDTA 480
  481 RLIWGKNLVA NCVRALEISA MEQVRDAWQT QKMHQSGKVS PEMASNLAGR QLTSAAIAHA 540
  541 HAFFTRNALE QVEALRKKGD LSPNVSLILG QLVELFVIDT FLRQSGCVLR WNNGITGTQL 600
  601 RFVERRFEEL LAKLRPNAVA LVDGFDFHDR VLGSTLGCHD GRVYERLMEE ARRNPINQEP 660
  661 VNSSFHNHLL PMMRGKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..677] PSI-BLAST 163.0 Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acyl-CoA oxidase activity
    		•  7.85164875699474 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  7.69964776555327 bayes_pls_golite062009
  • acyl-CoA dehydrogenase activity
    		•  6.0252876667118 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
    		•  5.50948952617422 bayes_pls_golite062009
  • palmitoyl-CoA oxidase activity
    		•  5.41720462605663 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.99827953439804 bayes_pls_golite062009
  • catalytic activity
    		•  2.41506805547596 bayes_pls_golite062009
  • pristanoyl-CoA oxidase activity
    		•  2.26651221125135 bayes_pls_golite062009
  • binding
    		•  0.749242681954192 bayes_pls_golite062009
  • protein binding
    		•  0.269787458920778 bayes_pls_golite062009
  • long-chain-acyl-CoA dehydrogenase activity
    		•  0.13696326544237 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle