Protein Overview: norpA-PA, norpA-...

General Information:
Name(s) found:	norpA-PE / FBpp0290690 [FlyBase] norpA-PA / FBpp0070619 [FlyBase] norpA-PB / FBpp0070618 [FlyBase]
Description(s) found: Found 41 descriptions. SHOW ALL	The gene no receptor potential A is referred to in FlyBase by the symbol Dmel\norpA (CG3620, FBgn0004625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4216659..4256487. It has the cytological map location 4B6-4C1. It is reported to have molecular function</span>: GTPase activator activity; phosphoinositide phospholipase C activity; phospholipase C activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: regulation of biological process; phospholipid metabolic process; phototransduction, visible light; organophosphate metabolic process; rhodopsin mediated phototransduction; phototransduction; primary metabolic process; immune response; lipid metabolic process; sensory perception of smell; regulation of developmental process; locomotory behavior; entrainment of circadian clock. 94 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; adult segment; compound cell cluster organ; adult brain; mouthpart; rhabdomere; integumentary plate; cell projection; multi-cell-component structure. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene no receptor potential A is referred to in FlyBase by the symbol Dmel\norpA (CG3620, FBgn0004625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4216659..4256487. It has the cytological map location 4B6-4C1. It is reported to have molecular function</span>: GTPase activator activity; phosphoinositide phospholipase C activity; phospholipase C activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: regulation of biological process; phospholipid metabolic process; phototransduction, visible light; organophosphate metabolic process; rhodopsin mediated phototransduction; phototransduction; primary metabolic process; immune response; lipid metabolic process; sensory perception of smell; regulation of developmental process; locomotory behavior; entrainment of circadian clock. 94 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; adult segment; compound cell cluster organ; adult brain; mouthpart; rhabdomere; integumentary plate; cell projection; multi-cell-component structure. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene no receptor potential A is referred to in FlyBase by the symbol Dmel\norpA (CG3620, FBgn0004625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4216659..4256487. It has the cytological map location 4B6-4C1. It is reported to have molecular function</span>: GTPase activator activity; phosphoinositide phospholipase C activity; phospholipase C activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: regulation of biological process; phospholipid metabolic process; phototransduction, visible light; organophosphate metabolic process; rhodopsin mediated phototransduction; phototransduction; primary metabolic process; immune response; lipid metabolic process; sensory perception of smell; regulation of developmental process; locomotory behavior; entrainment of circadian clock. 94 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; adult segment; compound cell cluster organ; adult brain; mouthpart; rhabdomere; integumentary plate; cell projection; multi-cell-component structure. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1095 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] inaD signaling complex [IPI][TAS] rhabdomere [IDA]
Biological Process:	diacylglycerol biosynthetic process [TAS] phospholipid biosynthetic process [TAS] phosphatidylinositol metabolic process [IMP] light-induced release of internally sequestered calcium ion [TAS] adult locomotory behavior [IMP] rhodopsin mediated phototransduction [IMP] phospholipid metabolic process [TAS] mucosal immune response [IMP] phototransduction [IMP][NAS][TAS] response to abiotic stimulus [IMP] intracellular signaling pathway [IEA] entrainment of circadian clock [IMP] negative regulation of compound eye retinal cell programmed cell death [IMP] elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [TAS] sensory perception of smell [IMP] phosphoinositide metabolic process [IMP] calcium-mediated signaling [TAS] deactivation of rhodopsin mediated signaling [IDA]
Molecular Function:	phosphoinositide phospholipase C activity [IEA][NAS][TAS] phospholipase C activity [TAS] calcium ion binding [IEA] GTPase activator activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKKYEFDWI IPVPPELTTG CVFDRWFENE KETKENDFER DALFKVDEYG FFLYWKSEGR  60
   61 DGDVIELCQV SDIRAGGTPK DPKILDKVTK KNGTNIPELD KRSLTICSNT DYINITYHHV 120
  121 ICPDAATAKS WQKNLRLITH NNRATNVCPR VNLMKHWMRL SYCVEKSGKI PVKTLAKTFA 180
  181 SGKTEKLVYT CIKDAGLPDD KNATMTKEQF TFDKFYALYH KVCPRNDIEE LFTSITKGKQ 240
  241 DFISLEQFIQ FMNDKQRDPR MNEILYPLYE EKRCTEIIND YELDEEKKKN VQMSLDGFKR 300
  301 YLMSDENAPV FLDRLDFYME MDQPLAHYYI NSSHNTYLSG RQIGGKSSVE MYRQTLLAGC 360
  361 RCVELDCWNG KGEDEEPIVT HGHAYCTEIL FKDCIQAIAD CAFVSSEYPV ILSFENHCNR 420
  421 AQQYKLAKYC DDFFGDLLLK EPLPDHPLDP GLPLPPPCKL KRKILIKNKR MKPEVEKVEL 480
  481 ELWLKGELKT DDDPEEDASA GKPPEAAAAP APAPEAAAAA EGAAEGGGGA EAEAAAANYS 540
  541 GSTTNVHPWL SSMVNYAQPI KFQGFDKAIE KNIAHNMSSF AESAGMNYLK QSSIDFVNYN 600
  601 KRQMSRIYPK GTRADSSNYM PQVFWNAGCQ MVSLNFQSSD LPMQLNQGKF EYNGGCGYLL 660
  661 KPDFMRRADK DFDPFADAPV DGVIAAQCSV KVIAGQFLSD KKVGTYVEVD MFGLPSDTVK 720
  721 KEFRTRLVAN NGLNPVYNED PFVFRKVVLP DLAVLRFGVY EESGKILGQR ILPLDGLQAG 780
  781 YRHVSLRTEA NFPMSLPMLF VNIELKIYVP DGFEDFMAML SDPRGFAGAA KQQNEQMKAL 840
  841 GIEEQSGGAA RDAGKAKEEE KKEPPLVFEP VTLESLRQEK GFQKVGKKQI KELDTLRKKH 900
  901 AKERTSVQKT QNAAIDKLIK GKSKDDIRND ANIKNSINDQ TKQWTDMIAR HRKEEWDMLR 960
  961 QHVQDSQDAM KALMLTVQAA QIKQLEDRHA RDIKDLNAKQ AKMSADTAKE VQNDKTLKTK1020
 1021 NEKDRRLREK RQNNVKRFME EKKQIGVKQG RAMEKLKLAH SKQIEEFSTD VQKLMDMYKI1080
 1081 EEEAYKTQGK TEFYA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..807]	PSI-BLAST	1000.0	No description for 2fjuB was found.
2	View Details	[808..1095]	PSI-BLAST	23.522879	Heavy meromyosin subfragment

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: norpA-PA, norpA-...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: