Protein Overview: Rala-PC, Rala-PA

General Information:
Name(s) found:	Rala-PC / FBpp0070559 [FlyBase] Rala-PA / FBpp0070558 [FlyBase]
Description(s) found: Found 40 descriptions. SHOW ALL	The gene Ras-related protein is referred to in FlyBase by the symbol Dmel\Rala (CG2849, FBgn0015286). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3599017..3613665. It has the cytological map location 3E5-3E6. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: innate immune response. 27 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; adult segment; adult mesothoracic segment; sensillum; adult external prothorax; wing hair; external compound sense organ; humeral trabecule; thoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene Ras-related protein is referred to in FlyBase by the symbol Dmel\Rala (CG2849, FBgn0015286). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3599017..3613665. It has the cytological map location 3E5-3E6. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: innate immune response. 27 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; adult segment; adult mesothoracic segment; sensillum; adult external prothorax; wing hair; external compound sense organ; humeral trabecule; thoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	201 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA] plasma membrane [IDA]
Biological Process:	dorsal closure [NAS] small GTPase mediated signal transduction [IEA] innate immune response [IDA] border follicle cell migration [IMP] negative regulation of JNK cascade [TAS]
Molecular Function:	GTP binding [IEA] GTPase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKPTAGPA LHKVIMVGSG GVGKSALTLQ FMYDEFVEDY EPTKADSYRK KVVLDGEEVQ  60
   61 IDILDTAGQE DYAAIRDNYF RSGEGFLCVF SITDDESFQA TQEFREQILR VKNDESIPFL 120
  121 LVGNKCDLND KRKVPLSECQ LRAQQWAVPY VETSAKTREN VDKVFFDLMR EIRSRKTEDS 180
  181 KATSGRAKDR CKKRRLKCTL L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..201]	PSI-BLAST	43.30103	Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.76

Protein Overview: Rala-PC, Rala-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: