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Protein Overview: FBpp0304837, CG3...

General Information:
Name(s) found: FBpp0304837 [FlyBase]
CG3573-PA / FBpp0070304 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • type=protein; loc=X:join(1817791..1817898,1818132..1818318,1818561..1818822,1818884..1819069,1819136..1819468,1819536..1820412,1820479..1820665,1820727..1820951,1821012..1821199); ID=FBpp0304837; name=Ocrl-PB; parent=FBgn0023508,FBtr0332586; dbxref=REFSEQ:NP_001259153,GB_protein:AGB94999,FlyBase:FBpp0304837,FlyBase_Annotation_IDs:CG3573-PB; MD5=e15420304369d18beee2914d4748b57c; length=850; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG3573 (CG3573, FBgn0023508). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1817038..1821555. It has the cytological map location 2B16. Based on sequence similarity, it is predicted to have molecular function</span>: inositol-polyphosphate 5-phosphatase activity. It is reported to be involved in the biological process</span>: dephosphorylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 850 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: signal transduction [IEA]
    dephosphorylation [NAS]
    Molecular Function: inositol trisphosphate phosphatase activity [NAS]
    inositol or phosphatidylinositol phosphatase activity [IEA]
    inositol-polyphosphate 5-phosphatase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTLSEAVAN GTATAATRTT KDIVKERFKE DETIEYIFEA YQIKGPEYSN RLLALVSSQS  60
   61 GGTFAIIAFS YLRTPLSSAN ELIINKVFAI DHNFQLRQDS KSSITTQQFD LSTAEDGPIK 120
  121 YYYYATESHH YEEFVAKVIS FKSTMAQHDP ETVLNFRWLN DYRQIGEVKQ ELKKRESEYI 180
  181 VYKDIIIYCA TWNVNNKTCS DSNNPLRAWL ACSEKPPDIY AIGLQELDTP TKAMLNSTQV 240
  241 QAIEKQWIDK MMDSVHPDVE YEILMSHRLV ATMLTVIVRK QLRQHIIRCR PKSVARGIFN 300
  301 TLGNKGGVAI SLQLNEGNIC FVNSHLAAHM GYVEERNQDY NAIVEGIRFD DGRTISDHDH 360
  361 IFWVGDLNYR IQEPPGQQRP GPLSDAQTYE LLLQYDQLRQ EMRRGKCFEG YTEGEIKFRP 420
  421 TYKYDPGTDN YDSSEKQRAP AYCDRVLWKG TRIEQLAYNS IMEIRQSDHK PVYAVFQVKV 480
  481 KTRDEVKYKR VQEEVLKAVD KRENDNQPQI NVEKTVIDFG TVRFNEPSTR DFNVYNNCPL 540
  541 PVDFSFKEKD IHAICEPWLH VDPRQDSLLI DSARSIRLKM NANVRTIAGL LRKIRASDNF 600
  601 DILILHVENG RDIFITVTGD YQPSCFGLSM ETMCRTDRPL SEYSQDQIKQ LMNDESPEYR 660
  661 VTMPREFFLL IDYLYRQGSK QVGAFPSYDS RLSLGAQFNS VRDWLDTWSD DPFPANAETA 720
  721 AQALLLLLDL PEHALLEPVV ENLLECTNKS QAMDYISLLS PPKRNVFMHL CMFLRAGIES 780
  781 QFYDLHQVAS TFGRILLRST ERAAWMDYHS RCIQFMRLFI DTDVEAMGNG NEGAGTGTGS 840
  841 GSGTRAGLQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] MSA 22.162997 View MSA. No confident structure predictions are available.
    2 View Details [141..409] PSI-BLAST 80.69897 Synaptojanin, IPP5C domain
    3 View Details [410..506] FFAS03 5.37 Synaptojanin, IPP5C domain
    4 View Details [507..850] PSI-BLAST 32.0 No description for 2qv2A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity, acting on ester bonds
    		•  6.16986356176974 bayes_pls_golite062009
  • phosphatase activity
    		•  5.90350467872925 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  5.84927924311254 bayes_pls_golite062009
  • phosphatidylinositol bisphosphate phosphatase activity
    		•  5.76202422677892 bayes_pls_golite062009
  • phosphoinositide 5-phosphatase activity
    		•  5.57319461575586 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
    		•  5.57319461575586 bayes_pls_golite062009
  • inositol-polyphosphate 5-phosphatase activity
    		•  4.20215185632047 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  3.88924621938812 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  3.07322777760243 bayes_pls_golite062009
  • inositol trisphosphate phosphatase activity
    		•  2.32855198081691 bayes_pls_golite062009
  • phosphatidylinositol-3-phosphatase activity
    		•  1.98439062808392 bayes_pls_golite062009
  • hydrolase activity
    		•  1.94088348434922 bayes_pls_golite062009
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
    		•  1.85311065741598 bayes_pls_golite062009
  • catalytic activity
    		•  1.76511376991978 bayes_pls_golite062009
  • phosphatidylinositol trisphosphate phosphatase activity
    		•  1.43486520454637 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.24865228320008 bayes_pls_golite062009
  • binding
    		•  1.10604548818653 bayes_pls_golite062009
  • phosphatidylinositol-4-phosphate phosphatase activity
    		•  1.01103192743992 bayes_pls_golite062009
  • phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
    		•  1.01103192743992 bayes_pls_golite062009
  • protein binding
    		•  0.476649214025345 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.469778612465362 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.466524009072462 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.414974033231176 bayes_pls_golite062009
  • exonuclease activity
    		•  0.408287239827419 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0598411724292803 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.05156428207806 bayes_pls_golite062009
  • nuclease activity
    		•  0.0418316891203612 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle