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View Structure Prediction Details

Protein: FBpp0304837, CG3...
Organism: Drosophila melanogaster
Length: 850 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0304837, CG3....

Description E-value Query
Range
Subject
Range
gi|125981035, gi... - gi|54642833|gb|EAL31577.1| GA17531-PA [Drosophila pseudoobscura], gi|125981035|ref|XP_001354524.1| G...
568.0 [0..1] [837..1]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTLSEAVAN GTATAATRTT KDIVKERFKE DETIEYIFEA YQIKGPEYSN RLLALVSSQS  60
   61 GGTFAIIAFS YLRTPLSSAN ELIINKVFAI DHNFQLRQDS KSSITTQQFD LSTAEDGPIK 120
  121 YYYYATESHH YEEFVAKVIS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [141-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKSTMAQHDP ETVLNFRWLN DYRQIGEVKQ ELKKRESEYI VYKDIIIYCA TWNVNNKTCS  60
   61 DSNNPLRAWL ACSEKPPDIY AIGLQELDTP TKAMLNSTQV QAIEKQWIDK MMDSVHPDVE 120
  121 YEILMSHRLV ATMLTVIVRK QLRQHIIRCR PKSVARGIFN TLGNKGGVAI SLQLNEGNIC 180
  181 FVNSHLAAHM GYVEERNQDY NAIVEGIRFD DGRTISDHDH IFWVGDLNYR IQEPPGQQRP 240
  241 GPLSDAQTYE LLLQYDQLRQ EMRRGKCFE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.69897
Match: 1i9yA
Description: Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on ester bonds 6.16986356176974 bayes_pls_golite062009
phosphatase activity 5.90350467872925 bayes_pls_golite062009
phosphoric ester hydrolase activity 5.84927924311254 bayes_pls_golite062009
phosphatidylinositol bisphosphate phosphatase activity 5.76202422677892 bayes_pls_golite062009
phosphoinositide 5-phosphatase activity 5.57319461575586 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 5.57319461575586 bayes_pls_golite062009
inositol-polyphosphate 5-phosphatase activity 4.20215185632047 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 3.88924621938812 bayes_pls_golite062009
lipid phosphatase activity 3.07322777760243 bayes_pls_golite062009
inositol trisphosphate phosphatase activity 2.32855198081691 bayes_pls_golite062009
phosphatidylinositol-3-phosphatase activity 1.98439062808392 bayes_pls_golite062009
hydrolase activity 1.94088348434922 bayes_pls_golite062009
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1.85311065741598 bayes_pls_golite062009
catalytic activity 1.76511376991978 bayes_pls_golite062009
phosphatidylinositol trisphosphate phosphatase activity 1.43486520454637 bayes_pls_golite062009
deoxyribonuclease activity 1.24865228320008 bayes_pls_golite062009
binding 1.10604548818653 bayes_pls_golite062009
phosphatidylinositol-4-phosphate phosphatase activity 1.01103192743992 bayes_pls_golite062009
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity 1.01103192743992 bayes_pls_golite062009
protein binding 0.476649214025345 bayes_pls_golite062009
exodeoxyribonuclease activity 0.469778612465362 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.466524009072462 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.414974033231176 bayes_pls_golite062009
exonuclease activity 0.408287239827419 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.0598411724292803 bayes_pls_golite062009
GTPase regulator activity 0.05156428207806 bayes_pls_golite062009
nuclease activity 0.0418316891203612 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [410-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYTEGEIKFR PTYKYDPGTD NYDSSEKQRA PAYCDRVLWK GTRIEQLAYN SIMEIRQSDH  60
   61 KPVYAVFQVK VKTRDEVKYK RVQEEVLKAV DKRENDN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.37
Match: 1i9yA
Description: Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [507-850]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPQINVEKTV IDFGTVRFNE PSTRDFNVYN NCPLPVDFSF KEKDIHAICE PWLHVDPRQD  60
   61 SLLIDSARSI RLKMNANVRT IAGLLRKIRA SDNFDILILH VENGRDIFIT VTGDYQPSCF 120
  121 GLSMETMCRT DRPLSEYSQD QIKQLMNDES PEYRVTMPRE FFLLIDYLYR QGSKQVGAFP 180
  181 SYDSRLSLGA QFNSVRDWLD TWSDDPFPAN AETAAQALLL LLDLPEHALL EPVVENLLEC 240
  241 TNKSQAMDYI SLLSPPKRNV FMHLCMFLRA GIESQFYDLH QVASTFGRIL LRSTERAAWM 300
  301 DYHSRCIQFM RLFIDTDVEA MGNGNEGAGT GTGSGSGTRA GLQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 2qv2A
Description: No description for 2qv2A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle