Protein Overview: CG42666-PF, CG42...

General Information:
Name(s) found:	CG42666-PF / FBpp0291799 [FlyBase] CG42666-PA / FBpp0291797 [FlyBase] CG42666-PC / FBpp0291796 [FlyBase]
Description(s) found: Found 35 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG42666 (CG42666, FBgn0261548).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1719693..1746966. It has the cytological map location 2B10-2B12. Based on sequence similarity, it is predicted to have molecular function</span>: exonuclease activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] This gene is referred to in FlyBase by the symbol Dmel\CG42666 (CG42666, FBgn0261548).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1719693..1746966. It has the cytological map location 2B10-2B12. Based on sequence similarity, it is predicted to have molecular function</span>: exonuclease activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] This gene is referred to in FlyBase by the symbol Dmel\CG42666 (CG42666, FBgn0261548).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1719693..1746966. It has the cytological map location 2B10-2B12. Based on sequence similarity, it is predicted to have molecular function</span>: exonuclease activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	761 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	NONE FOUND
Molecular Function:	nucleic acid binding [IEA] exonuclease activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHFFLEDFLQ AHLPKIYDKM QSCNKNSSSR ITTTNNNVTT TSNISGNSSN KRCPQKYTGN  60
   61 TLAVNSNMLA YQQQATAGGK NSTRKSRHNN NKQNHQQQQQ QQQQQFDHIH KRNGTAGGTG 120
  121 SECSPAAPTS NWLQRGYGRQ FVHSSCIEDK LLGHHNPGHR NSTSSDATSE DIDSSSELPN 180
  181 KSKGNSCAGS IHASGGSKSR SKRHQKQSGQ QTRNPDHNGQ RTGAATPCTG QKAKQGNAKW 240
  241 RQQQPNPSSN NQQQQMQQQM QQQKRGRNKK PGKWSNNIID NPNSNHGGSS QQKTCDSSSS 300
  301 SALSSPTSSA TTSATSSPTN SPTSYPRANG NRKRIEAALE WRREQELGRQ NANFLVPPLR 360
  361 QYEQLEFDDK TVVQQLRRHI IDNHLLRVYG FPVDSVVHEG AIEIFKCMPH MSFAAALAET 420
  421 AQAVTVINYH DGLTNRAEEE VANSTDSGNS SPQSLDSESG GEWSGSECES SNSSSSSAGE 480
  481 AALGLELKYC HFVPVERSLS KPCARCKRHF LVDELTGQYL THEECQYHSG KYQRYYDGVS 540
  541 HGRWTCCNEG EESSPGCCLG DRHVWSGSVV GVNGPYYDFV RTEHRGSGED EPAVYALDCE 600
  601 MSYTGRGLDV TKVSLVALNG QLVYEHFVRP VCDIIDYNTQ YSGITETDLC SGAKSLAEVQ 660
  661 RDLLQLITAD TILIGHGLEN DLRALRLVHN TLIDTSISFP HCNGFPYRRA LRHLTKVHLK 720
  721 RDIQAGDGTT GHSSFEDSRA CMELMLWRVN RELDPAWSWD D

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
ribonuclease activity	5.30591758406946	bayes_pls_golite062009
exoribonuclease activity	3.71639182685131	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	3.59362615133405	bayes_pls_golite062009
3'-5'-exoribonuclease activity	3.1992647486402	bayes_pls_golite062009
exonuclease activity	3.13676176369406	bayes_pls_golite062009
nuclease activity	3.11657409772275	bayes_pls_golite062009
ribonuclease H activity	2.91966688044755	bayes_pls_golite062009
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity	2.75003136922541	bayes_pls_golite062009
endonuclease activity	2.63074055051349	bayes_pls_golite062009
endoribonuclease activity	2.59247838057313	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.57498413015114	bayes_pls_golite062009
hydrolase activity	2.41899414621161	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2.04408785855894	bayes_pls_golite062009
3'-5' exonuclease activity	1.44123900197846	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
nucleic acid binding	1.23371034593624	bayes_pls_golite062009
protein binding	1.16870279238939	bayes_pls_golite062009
deoxyribonuclease activity	1.1219517187744	bayes_pls_golite062009
transcription regulator activity	1.10433412699603	bayes_pls_golite062009
DNA binding	0.860359347662869	bayes_pls_golite062009
binding	0.762139256580538	bayes_pls_golite062009
DNA polymerase activity	0.717600245625866	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	0.708753843279937	bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.598360955770972	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.568273228950698	bayes_pls_golite062009
	0.49473250705373	bayes_pls_golite062009
transcription factor activity	0.332903382446869	bayes_pls_golite062009
exodeoxyribonuclease activity	0.278838342302102	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.261428436029202	bayes_pls_golite062009
structure-specific DNA binding	0.0701825322473915	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.00214157813118243	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..93]	deduced	N/A	No confident structure predictions are available.
2	View Details	[94..228]	MSA	2.226993	View MSA. No confident structure predictions are available.
3	View Details	[229..434]	MSA	1.227988	View MSA. No confident structure predictions are available.
4	View Details	[435..495]	deduced	N/A	No confident structure predictions are available.
5	View Details	[496..565]	FFAS03	0.956	THE CRYSTAL STRUCTURE OF A ZINC FINGER - RNA COMPLEX REVEALS TWO MODES OF MOLECULAR RECOGNITION
6	View Details	[566..761]	PSI-BLAST	46.221849	human ISG20

Protein Overview: CG42666-PF, CG42...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: