Protein Overview: CG11403-PA

General Information:
Name(s) found:	CG11403-PA / FBpp0070235 [FlyBase]
Description(s) found: Found 24 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG11403 (CG11403, FBgn0026876). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1130906..1133925. It has the cytological map location 1E5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent DNA helicase activity; helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nucleotide-excision repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	861 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	nucleotide-excision repair [ISS] nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
Molecular Function:	DNA binding [IEA] ATP binding [IEA] helicase activity [ISS] ATP-dependent DNA helicase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQYTPNQRL DTPGAQEFGF PYSPYEIQEQ LMQELFQVLE RGQVGIFESP TGTGKSLTLT  60
   61 CGALTWLARH EELVRTEMLA RIRGVEQELA KLKEESEQSS NWLESQGKSR AQRAELLRLQ 120
  121 HLQALLDKQE QQLDQIRKGA KKHKRQGRVH PGKLEELEKD LDPESDSDSE HETADGPQEA 180
  181 AEDRYRPVQI FFCSRTHSQL AQIVAELRKT PHGQSVRSIS LGSRQQLCGN PAVRKLKHVG 240
  241 LMNERCLDMA TKKARPNPSK KSRLTAEANS RCPFKAASLV ESLRDLALTE PLDIEELANE 300
  301 GTACGGCSYY ASRSAVEHAQ LILLPYQLLL QKSARNQLGI SLKGSIVIVD EAHNLLDSVA 360
  361 QLHGSEISRQ QLERAKVQIS GYKDHFQKRF TTKNLLKINQ IIFIIRRLLK ILDQRKELQS 420
  421 NGCSMMRTYE LTAEGDFFNI DLCELLDFCA RTRFARKVQG RADRMEREPR PSENQAPVST 480
  481 ARSLILQRLA SEQKLKEKTK SVKRRVEDIN KEDKAEELQE QQKPTKKPVE EVAPSPIRPL 540
  541 LAFLETLTSN AEDGRILVDP VGGTLKYILL DPAEQFADIV AEARAIVIAG GTMQPTKELK 600
  601 EQLFTGCHDR LVERFYNHVV ANDAILPFVI SNGPSGAPLS FKFAHRGSAE MLRELSMILR 660
  661 NLCQVVPGGV VCFLPSYEYL DKVYKYLEQS GTLETISGRK SVFREVSGSA EQLLDNYALA 720
  721 IKRPASYGAL LLSVVGGKLS EGLNFADDLG RAVLVVGLPY SNSLSPELRQ RMQHLDEKLG 780
  781 PGAGNEYYEN LCVKAVNQCI GRAVRHIKDY ACVYLLDKRF ADPKIRGKLP KWISRHIVEA 840
  841 NAANGGFGAV QGRTARFFKG R

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
binding	2.5815673740955	bayes_pls_golite062009
DNA-dependent ATPase activity	2.51056345830226	bayes_pls_golite062009
nucleic acid binding	2.48860356580237	bayes_pls_golite062009
transcription regulator activity	2.12472659433935	bayes_pls_golite062009
DNA binding	2.11486163652443	bayes_pls_golite062009
DNA helicase activity	2.07805757910215	bayes_pls_golite062009
ATP-dependent DNA helicase activity	1.67733655597151	bayes_pls_golite062009
microtubule motor activity	1.60306634304093	bayes_pls_golite062009
motor activity	1.58540624011199	bayes_pls_golite062009
pyrophosphatase activity	1.53962350366788	bayes_pls_golite062009
helicase activity	1.47239452959713	bayes_pls_golite062009
structure-specific DNA binding	1.16901233264734	bayes_pls_golite062009
DNA-directed DNA polymerase activity	1.10767079010625	bayes_pls_golite062009
protein-DNA loading ATPase activity	1.08879865673064	bayes_pls_golite062009
DNA polymerase activity	1.07616364844317	bayes_pls_golite062009
double-stranded DNA binding	0.991867487042149	bayes_pls_golite062009
ATP-dependent helicase activity	0.962068859908115	bayes_pls_golite062009
purine NTP-dependent helicase activity	0.962068859908115	bayes_pls_golite062009
catalytic activity	0.942640875796745	bayes_pls_golite062009
transcription factor activity	0.927390204819289	bayes_pls_golite062009
DNA clamp loader activity	0.921329005784985	bayes_pls_golite062009
transcription repressor activity	0.908099102618053	bayes_pls_golite062009
single-stranded DNA binding	0.49639867125315	bayes_pls_golite062009
DNA strand annealing activity	0.270438185987508	bayes_pls_golite062009
protein binding	0.201869978778282	bayes_pls_golite062009
mismatched DNA binding	0.143486155092556	bayes_pls_golite062009
structural constituent of ribosome	0.0988428757344488	bayes_pls_golite062009
histone methyltransferase activity (H3-K9 specific)	0.0566193386200338	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..861]	FFAS03	1.43	No description for 2p6rA was found.

Protein Overview: CG11403-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: