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Protein Overview: TfIIA-S-2-PA

General Information:
Name(s) found: TfIIA-S-2-PA / FBpp0070177 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene TfIIA-S-2 is referred to in FlyBase by the symbol Dmel\TfIIA-S-2 (CG11639, FBgn0040338). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:905134..905676. It has the cytological map location 1E1. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 107 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    transcription factor TFIIA complex [ISS]
    Biological Process: transcription initiation from RNA polymerase II promoter [ISS]
    regulation of transcription from RNA polymerase II promoter [NAS]
    Molecular Function: general RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYQHYRATT LGRTLQDTLD EMMERGDITK KIANLVLLRY DKSISTALKD HGTSNMSFTA  60
   61 ERLETFRCCD NVWTLILKDA EFREDQHSLK VDVVKIVACL GTDNGNE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 40.0 HUMAN TFIIA/TBP/DNA COMPLEX

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  10.9702263885595 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  5.06993130505706 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.7915315980149 bayes_pls_golite062009
  • transcription activator activity
    		•  2.75298328621175 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.26583234267697 bayes_pls_golite062009
  • DNA binding
    		•  2.12151270115091 bayes_pls_golite062009
  • transcription coactivator activity
    		•  2.10703866415858 bayes_pls_golite062009
  • binding
    		•  1.9212205923594 bayes_pls_golite062009
  • protein binding
    		•  1.54756881357956 bayes_pls_golite062009
  • transcription factor binding
    		•  1.31659763916181 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.15899255380593 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle