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Protein Overview: l(1)sc-PA

General Information:
Name(s) found: l(1)sc-PA / FBpp0070073 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene lethal of scute is referred to in FlyBase by the symbol Dmel\l(1)sc (CG3839, FBgn0002561). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:303756..304850. It has the cytological map location 1B1. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; protein heterodimerization activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 19 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; primordium; germ layer; adult segment; portion of tissue; adult mesothoracic segment; ventral nerve cord primordium; larval head segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 257 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: myoblast cell fate determination [TAS]
    ventral cord development [TAS]
    central nervous system development [NAS]
    peripheral nervous system development [NAS]
    neuroblast fate determination [NAS][TAS]
    regulation of transcription [IEA]
    regulation of transcription from RNA polymerase II promoter [ISS]
    Molecular Function: transcription factor activity [NAS]
    protein heterodimerization activity [IPI]
    specific RNA polymerase II transcription factor activity [ISS]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSICSSKFQ QQHYQLTNSN IFLLQHQHHH QTQQHQLIAP KIPLGTSQLQ NMQQSQQSNV  60
   61 GPMLSSQKKK FNYNNMPYGE QLPSVARRNA RERNRVKQVN NGFVNLRQHL PQTVVNSLSN 120
  121 GGRGSSKKLS KVDTLRIAVE YIRGLQDMLD DGTASSTRHI YNSADESSND GSSYNDYNDS 180
  181 LDSSQQFLTG ATQSAQSHSY HSASPTPSYS GSEISGGGYI KQELQEQDLK FDSFDSFSDE 240
  241 QPDDEELLDY ISSWQEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] deduced N/A No confident structure predictions are available.
    2 View Details [78..169] PSI-BLAST 14.522879 Myc prot-oncogene protein
    3 View Details [170..257] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle