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Protein Overview: G9a-PA

General Information:
Name(s) found: G9a-PA / FBpp0070062 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene G9a is referred to in FlyBase by the symbol Dmel\G9a (CG2995, FBgn0040372). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:140040..148058. It has the cytological map location 1A1. There is experimental evidence that it has the molecular function</span>: histone-lysine N-methyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: ecdysone receptor-mediated signaling pathway; wing disc development; instar larval or pupal development. 40 alleles are reported. The phenotypes of these alleles are annotated with: wing; puparial operculum. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1637 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    euchromatin [IDA]
    Biological Process: chromatin modification [IEA]
    wing disc development [IMP]
    ecdysone receptor-mediated signaling pathway [IGI]
    instar larval or pupal development [IMP]
    Molecular Function: zinc ion binding [IEA]
    histone-lysine N-methyltransferase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDFVELMNS MSSTFNSDCA TSTAEGGTLL NLNLAEDKTL KWRNLANNQF ASKEKKHKDK  60
   61 EEEERKEARN QEEIEDIKAL LADVVDAAAV KLEEEEAQNA EKVEPHTKCE IEEEGRKEME 120
  121 YDQDVAKQDS EMEKKQNGKA TSITVKMESN ERAEKHATEI ATTSTERWEN ESFKTEQQNK 180
  181 KAAEKEEEPI LAATQKLEAN AEPLTTTRIE VAVASPLVVS SASVKLAADA TNQMRAATSA 240
  241 GAATLADKNV QVSPGGTRRS RRTPRPIDTP TSVTDEHVQV ENKKFGKSEQ YTDCSSHLER 300
  301 FTLDDNTAIV RLQLKSEPDK PSLTALSPEE NSAPAPKRGR GRARKIRPDA EVETSEVILP 360
  361 CEDSLGEKKP GRKRKLPDEP IDQQQLSDLV VVKTEQEELG DAPLGDVKRM RRSVRLGNRL 420
  421 HADGSPWEEV KTEALHPQPS AELSFAEVTS EILPLAVLDE KTPPKKRGRK AKTPCVKLES 480
  481 ETSCGLPFAN GNKKTNSSGG CELQLPKRSK RRIKPTPKIL ENDELRCEFE TKHIERMTQW 540
  541 ESAAAVDGDF ETPTTGGNGS NSSTSRQKSD KSDGSNFEGG PGHPAGTSAI KKRLFSKSQR 600
  601 DIENYGAAML AKSKLPPCPD VEQFLNDIKA SRINANRSPE ERKLNKKQQR KLAKQKEKHL 660
  661 KHLGLQKNHR DEPSDNDSSN TDNEFFPTTR VQVGKPSVTL RVRNSVTKEL PTTATLKSRR 720
  721 NPVVQAAKLT RRIGARAAGE VTEAARASVP ISTPDAEQLH SLDTSIQADV TPIRDLDMRP 780
  781 STSRVSKFIC LCQKPSQYYA RNAPDSSYCC AIDHIDDQKI GCCNELSSEV HNLLRPSQRV 840
  841 SYMILCDEHK KRLQSHNCCA GCGIFCTQGK FVLCKQQHFF HPDCAQRFIL STSYEKELGD 900
  901 EEDQGVKFSS PVLVLKCPHC GLDTPERTST VTMKCQSLPV FLRTQKYKIK PARLTTSSHL 960
  961 TQFGTVENAN TPGATARNKG GLSTAVTLSA ASSPASKTNG AQRGRAGTSN SNSRHALNSI1020
 1021 NFAQLIPESV MNVVLRGHVV SASGRVTAEF TPRDMYYAVQ NDDLERVAEI LAADFNVLTP1080
 1081 IREYLNGTCL HLVAHSGTLQ MAYLLLCKGA SSPDFVNIVD YELRTALMCA VMNEKCDMLN1140
 1141 LFLQCGADVA IKGPDGKTSL HIAAQLGNLE ATQLIVDSYR TSRNITSFLS FIDAQDEGGW1200
 1201 TAMVWAAELG HTDIVSFLLN QDADPNICDN DNNTVLHWST LHNDGLDTIT VLLQSGADCN1260
 1261 VQNVEGDTPL HIACRHSVTR MCIALIANGA DLMIKNKAEQ LPFDCIPNEE SECGRTVGFN1320
 1321 MQMRSFRPLG LRTFVVCADA SNGREARPIQ VVRNELAMSE NEDEADSLMW PDFRYVTQCI1380
 1381 IQQNSVQIDR RVSQMRICSC LDSCSSDRCQ CNGASSQNWY TAESRLNADF NYEDPAVIFE1440
 1441 CNDVCGCNQL SCKNRVVQNG TRTPLQIVEC EDQAKGWGVR ALANVPKGTF VGSYTGEILT1500
 1501 AMEADRRTDD SYYFDLDNGH CIDANYYGNV TRFFNHSCEP NVLPVRVFYE HQDYRFPKIA1560
 1561 FFSCRDIDAG EEICFDYGEK FWRVEHRSCV GCRCLTTTCK YASQSSSTNA SPTNATTAPE1620
 1621 NETGTLSSTN TEKIGHA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] deduced N/A No confident structure predictions are available.
    2 View Details [206..351] MSA 1.108992 View MSA. No confident structure predictions are available.
    3 View Details [352..561] deduced N/A No confident structure predictions are available.
    4 View Details [562..663] deduced N/A No confident structure predictions are available.
    5 View Details [664..834] deduced N/A No confident structure predictions are available.
    6 View Details [835..1320] PSI-BLAST 104.0 Ankyrin-R
    7 View Details [1321..1637] PSI-BLAST 50.69897 No description for 2o8jA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • binding
    		•  2.60916417202222 bayes_pls_golite062009
  • protein binding
    		•  1.64872738860757 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.589753112911856 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.39098214168175 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.156667528524505 bayes_pls_golite062009
  • DNA binding
    		•  0.139886855398905 bayes_pls_golite062009
  • transcription factor binding
    		•  0.11440400380364 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle