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Protein Overview: CG2135-PA

General Information:
Name(s) found: CG2135-PA / FBpp0085217 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG2135 (CG2135, FBgn0039874). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27595015..27597575. It has the cytological map location 100D2. Based on sequence similarity, it is predicted to have molecular function</span>: beta-glucuronidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 686 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEA]
    Molecular Function: cation binding [IEA]
    beta-glucuronidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSHWMPVTC LLLGSLQVLL AYTENDFLVN ANRKELTDSP LFEYDNVRKP TPTKGLLYPR  60
   61 DSETREVRSL DGMWQLVRSD PYDPLQGIRE KWFMDALRKT GREIISMPVP ASYNDITTDN 120
  121 LRDHVGTVWY ERTFFVPRSW KTMQRTWLRF SSVHYSAVVW INGRNATSHS IGHLPFESEI 180
  181 SGLLSFGGDN RITVMCDNRL SNRTIPQGSV YKVATDDGTV PIQSYTFDFF NYAGIHRSVH 240
  241 LYTTPLLHIS DLEVTTQLTK EGLGRIDYRV WLDASKEGLQ IQPIQLRVQL RDKDGHVAAQ 300
  301 QINKAVYHGT LLVPNATPWW PYLMHSDPGY LYNLQFELFV ASNEKELESL QDTYRLPVGI 360
  361 RSLSWDNDSL LLNGKPLYLR GFGRHEDSDI RGKGLDNALL ARDFNLLKWT GANAYRTSHY 420
  421 PYSEESMQFA DQHGIMIIDE CPAVNIDIFE PQLLENHMSS LEQLIHRDRN HPSVVAWSVA 480
  481 NEPRSNKQGA LKYFEFLVNY VREIAHGRPL TAAINANSSS CHLAQFLDIV GFNRYNSWYQ 540
  541 NSGRTDMILN LLTIEAQSWR DRFGKPVIQF EYGGDTMEGM HSLPAFIWSE EYQVELFSRH 600
  601 FKAFDELRGR GWFIGEFVWN FADFRTAQTI TRVGGNKKGV FTRNRQPKEV AHILRRRYFA 660
  661 LAKELDMFGL PEDLTVYISK HIHNEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..686] PSI-BLAST 122.0 beta-Glucuronidase; beta-Glucuronidase, domain 3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  6.26329339735894 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.92180849080637 bayes_pls_golite062009
  • hydrolase activity
    		•  3.98075336331567 bayes_pls_golite062009
  • hexosaminidase activity
    		•  3.21852337137039 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  2.69072465526737 bayes_pls_golite062009
  • hyalurononglucosaminidase activity
    		•  2.33846657668199 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • glucosidase activity
    		•  1.85545420386612 bayes_pls_golite062009
  • galactosidase activity
    		•  1.26155841119987 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  1.00973231642658 bayes_pls_golite062009
  • peptidase activity
    		•  0.618122797487524 bayes_pls_golite062009
  • binding
    		•  0.601963252939415 bayes_pls_golite062009
  • beta-glucuronidase activity
    		•  0.55376725638834 bayes_pls_golite062009
  • sugar binding
    		•  0.52048704356718 bayes_pls_golite062009
  • mannosidase activity
    		•  0.48536369022293 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.340224150705178 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.31275257729319 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • fucose binding
    		•  0.0946432585122601 bayes_pls_golite062009
  • beta-galactosidase activity
    		•  0.0137149865738109 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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