YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: eIF2B-alpha-PA

General Information:
Name(s) found: eIF2B-alpha-PA / FBpp0084874 [FlyBase]
Description(s) found:
Found 24 descriptions.
SHOW ALL
  • The gene eIF2B-Ã?&#142;Ã?± is referred to in FlyBase by the symbol Dmel\eIF2B-Ã?&#142;Ã?± (CG7883, FBgn0039726). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25760304..25761598. It has the cytological map location 99C7. There is experimental evidence that it has the molecular function</span>: enzyme regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: cytosol [ISS]
    eukaryotic translation initiation factor 2B complex [ISS]
    Biological Process: translational initiation [ISS]
    Molecular Function: translation initiation factor activity [ISS]
    enzyme regulator activity [IGI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQITENGQD FDVVKYFLQL LDEDKDLSSG IAAIRTLLMI LEKKQFGTIH ILHTTMREAV  60
   61 AAMRNTDLSI AAIVSAGELF CRFITLSLDD KHMEECRQIM LNRGKIFLTK LLNSRQVIAQ 120
  121 QAQRFITDGC RILTHSRSRV VLKALITASQ NKKSFHVYVT QGGTGNSGEE MVKDLHAAGI 180
  181 DCTLILDSAT GYVMESVDFV LVGAEAVVES GGIINRIGTY TMGLCAREMK KPFYVLAESF 240
  241 KFSRLYPLNQ RDLPNEYKYS RKHLNDVSKV HPLVDYTPPV YITLLFTDLG RLTPSAVSDE 300
  301 LIKLYM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..306] PSI-BLAST 86.0 X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.1099993541596 bayes_pls_golite062009
  • translation regulator activity
    		•  5.74669335554405 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.17718456512191 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.9283980201455 bayes_pls_golite062009
  • DNA binding
    		•  1.55389679363348 bayes_pls_golite062009
  • binding
    		•  1.53908996868286 bayes_pls_golite062009
  • catalytic activity
    		•  1.31732715713197 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.09424756417577 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.03828732072006 bayes_pls_golite062009
  • transcription factor activity
    		•  0.995059566132783 bayes_pls_golite062009
  • sugar binding
    		•  0.319281682893106 bayes_pls_golite062009
  • protein binding
    		•  0.0293610121675921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle