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Protein Overview: CG11899-PA

General Information:
Name(s) found: CG11899-PA / FBpp0084759 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG11899 (CG11899, FBgn0014427). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25026174..25027492. It has the cytological map location 99A1. Based on sequence similarity, it is predicted to have molecular function</span>: O-phospho-L-serine:2-oxoglutarate aminotransferase activity. It is reported to be involved in the biological process</span>: pyridoxine biosynthetic process; L-serine biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 364 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: pyridoxine biosynthetic process [NAS]
    L-serine biosynthetic process [IEA][NAS]
    Molecular Function: pyridoxal phosphate binding [IEA]
    O-phospho-L-serine:2-oxoglutarate aminotransferase activity [ISS][NAS]
    catalytic activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVINFAAGPA KLPEEVLKEV QENLVNCNGS GISVMEMSHR SSNYAKIHDA TISDLRELLN  60
   61 VPSNYKILLM QGGGTGQFAA VALNLIGKTG TADYVITGSW SAKAAKEAAQ YGTVNAVLPK 120
  121 LAKYTTVPRQ ETWKLDPNAS YVYYCDNETV EGVEFDFVPE VPAGVPLVAD MSSNFLSRPF 180
  181 DVSKFGVIYA GAQKNIGPAG TTVIIVRDDL IGKHLKITPS ILNFEQMDKN NSLLNTPPTF 240
  241 GIYVMGLVFK WIKRNGGVAG MAKLAAAKSK LIYDTINQSN GFYYCPVDVN VRSRMNVPFR 300
  301 IGSASGDDAL EKEFLSKAEA EGMIQLKGHR SVGGIRASLY NAVTLAETQQ LANLMLAFYK 360
  361 NNKN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..364] PSI-BLAST 63.69897 Phosphoserine aminotransferase, PSAT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  2.1692959843619 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.80372125032222 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.80372125032222 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  1.42214433786345 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  0.81652984148807 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.636782746250952 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.526698053525422 bayes_pls_golite062009
  • DNA binding
    		•  0.516618701017633 bayes_pls_golite062009
  • binding
    		•  0.450641761940864 bayes_pls_golite062009
  • structural molecule activity
    		•  0.347975812448725 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • transcription factor activity
    		•  0.188693175079415 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle