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Protein Overview: wdb-PA, wdb-PE, ...

General Information:
Name(s) found: wdb-PE / FBpp0084579 [FlyBase]
wdb-PC / FBpp0084578 [FlyBase]
wdb-PA / FBpp0084577 [FlyBase]
FBpp0084575 [FlyBase]
wdb-PD / FBpp0084574 [FlyBase]
wdb-PB / FBpp0084573 [FlyBase]
Description(s) found:
Found 94 descriptions.
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  • The gene widerborst is referred to in FlyBase by the symbol Dmel\wdb (CG5643, FBgn0027492). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23390764..23407961. It has the cytological map location 98A6-98A8. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: chromosome segregation; spindle assembly. 41 alleles are reported. The phenotypes of these alleles are annotated with: eye; intersegmental nerve; tarsal segment; tormogen cell; wing hair. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene widerborst is referred to in FlyBase by the symbol Dmel\wdb (CG5643, FBgn0027492). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23390764..23407961. It has the cytological map location 98A6-98A8. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: chromosome segregation; spindle assembly. 41 alleles are reported. The phenotypes of these alleles are annotated with: eye; intersegmental nerve; tarsal segment; tormogen cell; wing hair. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene widerborst is referred to in FlyBase by the symbol Dmel\wdb (CG5643, FBgn0027492). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23390764..23407961. It has the cytological map location 98A6-98A8. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: chromosome segregation; spindle assembly. 41 alleles are reported. The phenotypes of these alleles are annotated with: eye; intersegmental nerve; tarsal segment; tormogen cell; wing hair. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • type=protein; loc=3R:complement(23391291..23391576,23391640..23391869,23391929..23392262,23392327..23392517,23392583..23392777,23392874..23393073,23393138..23393276); ID=FBpp0084575; name=wdb-PF; parent=FBgn0027492,FBtr0085205; dbxref=FlyBase:FBpp0084575,FlyBase_Annotation_IDs:CG5643-PF,GB_protein:AAN14117.1,REFSEQ:NP_733219,GB_protein:AAN14117; MD5=25d6e4ab70a2798b354026f2d8ca9f13; length=524; release=r5.56; species=Dmel; [FlyBase]
  • The gene widerborst is referred to in FlyBase by the symbol Dmel\wdb (CG5643, FBgn0027492). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23390764..23407961. It has the cytological map location 98A6-98A8. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: chromosome segregation; spindle assembly. 41 alleles are reported. The phenotypes of these alleles are annotated with: eye; intersegmental nerve; tarsal segment; tormogen cell; wing hair. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene widerborst is referred to in FlyBase by the symbol Dmel\wdb (CG5643, FBgn0027492). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23390764..23407961. It has the cytological map location 98A6-98A8. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: chromosome segregation; spindle assembly. 41 alleles are reported. The phenotypes of these alleles are annotated with: eye; intersegmental nerve; tarsal segment; tormogen cell; wing hair. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: protein phosphatase type 2A complex [ISS]
    Biological Process: spindle assembly [IMP]
    signal transduction [IEA]
    chromosome segregation [IMP]
    Molecular Function: protein serine/threonine phosphatase activity [ISS]
    protein phosphatase type 2A regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGTFVDRI DPFAKRSLKK KGKKSQGSSR YRNSQDVELQ QLPPLKADCS SLEQEELFIR  60
   61 KLRQCCVSFD FMDPVTDLKG KEIKRAALND LSTYITHGRG VLTEPVYPEI IRMISCNLFR 120
  121 TLPPSENPDF DPEEDDPTLE ASWPHLQLVY EVFLRFLESQ DFQATIGKRV IDQKFVLQLL 180
  181 ELFDSEDPRE RDFLKTVLHR IYGKFLGLRA FIRKQINNIF LRFIYETEHF NGVGELLEIL 240
  241 GSIINGFALP LKAEHKQFLV KVLLPLHKVK CLSLYHAQLA YCIVQFLEKD PFLTEPVVRG 300
  301 LLKFWPKTCS QKEVMFLGEI EEILDVIDPP QFVKIQEPLF RQIAKCVSSP HFQVAERALY 360
  361 LWNNEYAMSL IEENNAVIMP IMFPALYRIS KEHWNQTIVA LVYNVLKTFM EMNSKLFDEL 420
  421 TSSYKAERQK EKKRERDREE LWKKLHELES NRSSGRTAGG SATTSNSAAS AASTSLQPPS 480
  481 SAGLNSHQQQ SNSGSSGSLS SGGAGGDNNP ATTNAKIKQD KADN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..524] PSI-BLAST 1000.0 No description for 2nppB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.41566231556356 bayes_pls_golite062009
  • phosphatase activity
    		•  6.2815295903206 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  6.23975872771765 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.04343158483355 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.13001603767079 bayes_pls_golite062009
  • protein phosphatase type 2A regulator activity
    		•  4.9046120881035 bayes_pls_golite062009
  • phosphatase regulator activity
    		•  2.6399267580941 bayes_pls_golite062009
  • protein phosphatase regulator activity
    		•  2.60055057218296 bayes_pls_golite062009
  • binding
    		•  2.27902748675387 bayes_pls_golite062009
  • hydrolase activity
    		•  1.97016752220053 bayes_pls_golite062009
  • protein binding
    		•  1.94427330399472 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.261371469269675 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.226502465295366 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  0.0443887387331605 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0343779350724151 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0257259839107 bayes_pls_golite062009
  • kinase activity
    		•  0.0101018729931129 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.00105949493785734 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle