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Protein Overview: woc-PA

General Information:
Name(s) found: woc-PA / FBpp0084548 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene without children is referred to in FlyBase by the symbol Dmel\woc (CG5965, FBgn0010328). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23082315..23089758. It has the cytological map location 97E11. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription, DNA-dependent; ecdysone biosynthetic process; telomere capping. 13 alleles are reported. The phenotypes of these alleles are annotated with: lymph gland; chromosome, telomeric region; larval proventriculus; polytene chromosome; nuclear chromosome; hemocyte; imaginal disc; larval brain; ring gland; prothoracic gland. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1688 amino acids

    Gene Ontology:
    Cellular Component: heterochromatin [IDA]
    polytene chromosome, telomeric region [IDA]
    euchromatin [IDA]
    polytene chromosome interband [IDA]
    protein complex [IDA]
    Biological Process: regulation of transcription, DNA-dependent [IMP]
    telomere capping [IMP]
    ecdysone biosynthetic process [IMP]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IEA]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEISSLDSF GADSNARPES ATPRSEEQQD QDRQQTAPAA SETLDTPASP PAEDAAAQES  60
   61 KPPPSKEADD DFEQISEGSL DADDNQSRDK AASTPADPVD AEEPAEEPTP NEEPQGGEDE 120
  121 QPQTEAVRVD PQEEPEEAEE ETDALQATAE EVEAAAAEAD AVDGGPASPE AMDVDEGEVD 180
  181 AEGEAEQEAE DDAALDREAT DDVDMQSVGA DSHQAEDAEP PEGRDEVDTS LEEQENGQDP 240
  241 DEREKDAAAD EDDPDAEGDA ESEQVDENAE ETGEAEHGDD TVENVLEPEE SDVCLIPDDQ 300
  301 ETEVTEAEKE LARENAEKAA EEEEAEERQA KTPDNDRKSP ADAAADPEDD SAAAVDATDV 360
  361 SPTTPTADGV AAAANEEEAG GDVPDPDEPT AEESSSAGAG EPGSTPKIII SWIVGSVQKC 420
  421 KQCGDEKNCG FRYRSPEESE EMDKEKENDK AEENAEEGEE EEARQKPAAP SGFEYICDTA 480
  481 CVDALLEDQP GKYFVRRKKF LVEEVVREEG AAEAEASADG EGGDAEEEAT PANTQDCLQC 540
  541 KDKTRCKYFI KQDQDCFYIC NDDCFNLLNA EEPDKFKLKR HSIRVRNIGA TTLQPPQNSP 600
  601 TKRTDGSVVA RTVEEAETAR LDRIESFRRR CADCEADINT DEKQLMWETM DFCNEVCLGS 660
  661 YQRTIGSTCE TCKQEVSSIA LGKYCVRFGF DVRQFCCAGC LNTFKKGLKT CSCCQKDISG 720
  721 GQEGFLAPVG DKDQFKDFCS QSCLRRYESM CNPRRKLRTD VCGVCNNQKP VRVEMLLEDR 780
  781 EHYFCSNPCF SAFKFVSNVN ADPCAMCSKY FERRSAESYT IYNEQQSPKV FCSRVCINVY 840
  841 IIVNRHIVSC QWCKVKKYNF DMIYQIGGPH DQETLTCSIN CLTMHGVSCN ISARAVTKCD 900
  901 NCSNFNTPQY HLTMSDASMR NFCTYQCVMQ FQNQFARAPL TLDSDLPPSS AGSSKSQQQS 960
  961 NRGNKNAAPF PTGLPKRVKL KLSHTGKGGV GGKKSGSGTM LPVISTVQSL ASGETEARIG1020
 1021 NLTVRRKRGR PRESGTSSPP LSMPGVHPPA QRGRPRKHAV DYSARSPSPT MSGGSSHMGI1080
 1081 PVRRNTTTTM DFGPATVTET KIITVPPYPK AVRNVNISCK PLTVTQGEQC SPDVRDCATQ1140
 1141 TEKDYSNKVL IPVPVPIFVP QPMYMYSAPF PVPVPIPLPI PVPIFIPTTR NTAQGILKEI1200
 1201 KKIQDKMPED PLEAELLMMA EMVAEEKHES DSDSDNEIKP DPGLVALQYQ NSLESVAQQQ1260
 1261 QQQQVVDVSG AGHNPYGDDM LQIALKMATG DYDNHHQTST VDLETSMTAN TISSQSPMGH1320
 1321 DGMGQMGVHH LDQQHHMLDA TQRTARGRKR GVGVVMDPPN RNSRSPVKRQ RGGEMDHSAL1380
 1381 QQQSQQAQQP QEKPDAQMFL KYTFGVNAWK QWVMTKNADI EKSSMRRRPF KTELLQMTAD1440
 1441 ELNYSLCLFV KEVRKPNGTE YAPDTIYYLV LGIQQYLYVN GRIDNIFYDP YYERFTECLD1500
 1501 EVARKFSVLY NDSQYIVTRV EEEHLWECKQ LGAHSPHVLL STLMFFNTKH FNLTTVEEHM1560
 1561 QLSFSHIMKH WKRSSQNSKV PGSRNVLLRF YPPQAGLDAN PRKKKVYEQQ ENEENPLRCP1620
 1621 VRLYEFYLSK CPESVKTRND VFYLQPERSC VPDSPVWYST QALGQDALQR MLHRVKMVKE1680
 1681 INIALLTT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..416] PSI-BLAST 21.09691 Heavy meromyosin subfragment
    2 View Details [417..594] deduced N/A No confident structure predictions are available.
    3 View Details [595..914] PSI-BLAST 16.0 Transcription factor IIIA, TFIIIA
    4 View Details [915..1150] PSI-BLAST 40.69897 No description for 2i13A was found.
    5 View Details [1151..1312] deduced N/A No confident structure predictions are available.
    6 View Details [1313..1381] deduced N/A No confident structure predictions are available.
    7 View Details [1382..1688] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • chromatin binding
    		•  3.50591583802992 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.49465803051514 bayes_pls_golite062009
  • binding
    		•  2.47962305876847 bayes_pls_golite062009
  • DNA binding
    		•  2.45187248125336 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.16668329615638 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  2.1123891494681 bayes_pls_golite062009
  • histone binding
    		•  1.89970441780885 bayes_pls_golite062009
  • transcription factor activity
    		•  1.36935765588098 bayes_pls_golite062009
  • protein binding
    		•  0.905022998164426 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.69281285557277 bayes_pls_golite062009
  • transcription activator activity
    		•  0.55571422139212 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.425282485896749 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.311339098303136 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0320047263006993 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle