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Protein Overview: Dak1-PA

General Information:
Name(s) found: Dak1-PA / FBpp0084349 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • The gene Dak1 is referred to in FlyBase by the symbol Dmel\Dak1 (CG6092, FBgn0028833). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21879959..21882213. It has the cytological map location 96F10. There is experimental evidence that it has the molecular function</span>: cytidylate kinase activity; uridylate kinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 253 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
    Molecular Function: cytidylate kinase activity [IDA][ISS][NAS]
    uridylate kinase activity [IDA]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRALARTTL RAVANDCGSP GVGLAPSALT QHQLRHSKAS NRFITTTSTA PPHNIGIMSV  60
   61 EKPKIVFVLG GPGAGKGTQC SRIVDRFQFT HLSAGDLLRE ERSREGSEFG NLIEDYIRNG 120
  121 KIVPVEVTCS LLENAMKASG KSRFLIDGFP RNQDNLDGWN RQMSEKVDFQ FVLFFDCGED 180
  181 VCVKRCLGRG QSGSGRTDDN LDSLKKRIST YNNDSLPIIK FFEGAGQVKR IDASPDAEEV 240
  241 FGEVEKIFVA SGF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] FFAS03 1.41 No description for 2gesA was found.
    2 View Details [88..253] PSI-BLAST 39.0 Crystal structure of the human UMP/CMP kinase in open conformation

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  5.63633783771436 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  4.87013305162694 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  4.71956130169341 bayes_pls_golite062009
  • adenylate kinase activity
    		•  3.67594732794865 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  2.29455092461489 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.39044805677656 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.27520023113176 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.1237520329736 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.03581449013603 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • guanylate kinase activity
    		•  0.98934362137863 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.940135818362306 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.738234102557832 bayes_pls_golite062009
  • motor activity
    		•  0.68122766055454 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • CTP synthase activity
    		•  0.554689818807922 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.48522137429998 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • formate-tetrahydrofolate ligase activity
    		•  0.21533099279384 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009
  • structural molecule activity
    		•  0.0558641287316701 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.58

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle