YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: LpR2-PB

General Information:
Name(s) found: LpR2-PB / FBpp0084302 [FlyBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • The gene LpR2 is referred to in FlyBase by the symbol Dmel\LpR2 (CG31092, FBgn0051092). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21524488..21566187. It has the cytological map location 96E10-96F1. Based on sequence similarity, it is predicted to have molecular function</span>: low-density lipoprotein receptor activity. The biological processes in which it is involved are not known. 37 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 826 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: NONE FOUND
    Molecular Function: calcium ion binding [IEA]
    low-density lipoprotein receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPICRILGC SFLLLIAGLV PHHASRVVGL ESTCSQEQFR CGNGKCIPRR WVCDRENDCA  60
   61 DGSDESTSQC RGLCSSLMFM CKNGEQCIHR EFMCDGDQDC RDGSDELECG NRTCRSDEFT 120
  121 CGNGRCIQNR FKCDDDDDCG DGSDEKNCGE KAKCGSNFFA CKSGPCIPNQ WVCDGDSDCR 180
  181 NGEDEMQNCT VSLLNFCQAG EFQCSDRITC LHKSWVCDGE ADCPDGEDES QSNCLKVSCR 240
  241 PDQFQCNDQS CIAGHLTCNG KRDCADGSDE IMCDISATPR TCNATTEFDC GGGLCIPNAK 300
  301 VCNRRKDCPN GEDEPAGKCG INECSSKNGG CMHQCVNLEV GYRCECHDGY KLGADQHTCV 360
  361 DIDECETPGI CSQVCVNEIG AFKCECEAGY MRLLKNHTRC KASEGHASLL LARRHDIRKI 420
  421 ALDRPEMTSI VNSTKAATAL DFVFRTGMIF WSDVATQSIY KAPIDEGNDR TVVLTKSSVT 480
  481 SDGLAVDWIY NHVYFTDTHK CTIELTNFEG SMGKVLVKDS LDIPRSIALD PIEGWMYWSD 540
  541 WGASPRIERA GMDGTHRTAI ITYDVKWPNG ITLDLVQKRL YWVDGKLNTI SSSNYDGSQR 600
  601 HQVLYSGEYL RHPFSITTFE DYVYWTDWDK QAVFKANKFN GMDVEPVTAT HMLEHPMVVH 660
  661 VYHPYRQPDG VNHCQSVNGH CSHLCLPAPR INERSPRISC ACPTGLKLMP DGLMCVEDLE 720
  721 TKTGNNRTDT SNQVHKSDAE SENDYVEIAL HVIASLAGTA LVASVIYVVY RRCTRAVNSM 780
  781 NFENPVYHKT TEDHFSLEKN GTPHIYAAAN DEEAVNPLFK SGTECV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..718] PSI-BLAST 131.0 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    2 View Details [719..826] MSA 1.113984 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • very-low-density lipoprotein binding
    		•  7.75680908341624 bayes_pls_golite062009
  • very-low-density lipoprotein receptor activity
    		•  7.75680908341624 bayes_pls_golite062009
  • low-density lipoprotein binding
    		•  6.26591728596226 bayes_pls_golite062009
  • receptor activity
    		•  5.18957329214193 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  5.12821337870369 bayes_pls_golite062009
  • receptor binding
    		•  4.60755835611133 bayes_pls_golite062009
  • lipoprotein binding
    		•  4.14588039269064 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  4.1172010378646 bayes_pls_golite062009
  • growth factor activity
    		•  3.72526290796901 bayes_pls_golite062009
  • low-density lipoprotein receptor activity
    		•  3.65371958920557 bayes_pls_golite062009
  • lipoprotein receptor binding
    		•  3.5371428063122 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  3.52219710022937 bayes_pls_golite062009
  • lipoprotein receptor activity
    		•  3.27342368855237 bayes_pls_golite062009
  • apolipoprotein binding
    		•  3.15697162337516 bayes_pls_golite062009
  • heparin binding
    		•  3.15251810133854 bayes_pls_golite062009
  • binding
    		•  2.97929690141955 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.16844098063599 bayes_pls_golite062009
  • sterol transporter activity
    		•  2.16184949636569 bayes_pls_golite062009
  • protein binding
    		•  1.97546801934296 bayes_pls_golite062009
  • lipid transporter activity
    		•  1.91872326766441 bayes_pls_golite062009
  • lipoprotein transporter activity
    		•  1.72944996169507 bayes_pls_golite062009
  • transcription factor binding
    		•  1.71838409809333 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.68241417866789 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.66401431847753 bayes_pls_golite062009
  • signal transducer activity
    		•  1.66401431847753 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.61057978332614 bayes_pls_golite062009
  • high-density lipoprotein binding
    		•  1.52515316728946 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  1.45792086043869 bayes_pls_golite062009
  • transporter activity
    		•  1.44005597324471 bayes_pls_golite062009
  • collagen binding
    		•  1.3611207932336 bayes_pls_golite062009
  • protein transporter activity
    		•  1.27232657510644 bayes_pls_golite062009
  • pattern binding
    		•  1.26957983931218 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.11978732751628 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.08803800589535 bayes_pls_golite062009
  • protein kinase activity
    		•  1.00235965838736 bayes_pls_golite062009
  • apolipoprotein E binding
    		•  0.845204752730401 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.741912411452008 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.72748768329894 bayes_pls_golite062009
  • kinase activity
    		•  0.692244195382463 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.67022333774569 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  0.66981956037474 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.44857826904729 bayes_pls_golite062009
  • extracellular matrix binding
    		•  0.3265100728106 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle