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Protein Overview: FBpp0293748, msi...

General Information:
Name(s) found: FBpp0305820 [FlyBase]
FBpp0293748 [FlyBase]
msi-PB / FBpp0084255 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • type=protein; loc=3R:join(21345345..21345451,21389802..21389849,21400606..21400644,21420796..21421324,21425229..21425932,21425992..21426469); ID=FBpp0305820; name=msi-PF; parent=FBgn0011666,FBtr0333664; dbxref=REFSEQ:NP_001262960,GB_protein:AGB96340,FlyBase:FBpp0305820,FlyBase_Annotation_IDs:CG5099-PF; MD5=36cd1c70153af7868863bd58a1b2f2a1; length=634; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:join(21345345..21345451,21389802..21389849,21400606..21400644,21420796..21421324,21425229..21425932,21425992..21426469); ID=FBpp0293748; name=msi-PC; parent=FBgn0011666,FBtr0305218; dbxref=REFSEQ:NP_001247303,GB_protein:AFH06620,FlyBase:FBpp0293748,FlyBase_Annotation_IDs:CG5099-PC; MD5=36cd1c70153af7868863bd58a1b2f2a1; length=634; release=r5.56; species=Dmel; [FlyBase]
  • The gene musashi is referred to in FlyBase by the symbol Dmel\msi (CG5099, FBgn0011666). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21344045..21428143. It has the cytological map location 96E2-96E4. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: stem cell maintenance; germ-line stem cell division; negative regulation of translation. 22 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; testis sheath muscle; thecogen cell; testis; ommatidium; socket; external sensory organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 634 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of translation [TAS]
    stem cell maintenance [IMP]
    germ-line stem cell division [IMP]
    mRNA processing [ISS]
    negative regulation of translation [IMP][TAS]
    cell fate determination [TAS]
    Molecular Function: nucleotide binding [IEA]
    translation regulator activity [TAS]
    translation repressor activity, nucleic acid binding [TAS]
    mRNA binding [ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFENPAVAA KLPFPYNVPP PLQAAAAAAA AVPNLRFQTP IKAFACLTAA TRSVSEMNAT  60
   61 SLYAGNPMEN AAAAAAAAAA GLIDPHHNRD LHQALVASIA NNSVAAIGGG LTTAAVLKSA 120
  121 AQQSQQAVQQ NQNAVVVTPG LEQPKQEPAQ QAALALLKEN VNASAGAGQN NGQAAMGGSN 180
  181 KSGSSGRSTP SLSGGSGSDP APGKLFVGGL SWQTSSDKLK EYFNMFGTVT DVLIMKDPVT 240
  241 QRSRGFGFIT FQEPCTVEKV LKVPIHTLDG KKIDPKHATP KNRPRQANKT KKIFVGGVSQ 300
  301 DTSAEEVKAY FSQFGPVEET VMLMDQQTKR HRGFGFVTFE NEDVVDRVCE IHFHTIKNKK 360
  361 VECKKAQPKE AVTPAAQLLQ KRIMLGTLGV QLPTAPGQLI GARGAGVATM NPLAMLQNPT 420
  421 QLLQSPAAAA AAQQAALISQ NPFQVQNAAA AASIANQAGF GKLLTTYPQT ALHSVRYAPY 480
  481 SIPASAATAN AALMQAHQAQ SVAAAAHHHQ QQQQQQHHHQ QQTHNAHVAA AQQQQQSHHN 540
  541 AVSNPASQAH SAAAAAALAA NAANGAGAAG AHSLAAAAQQ AGLMAGNPLN AAAAAAAAAA 600
  601 NPAAAYSNYA LANVDMSSFQ GVDWSTMYGM GMYV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] PSI-BLAST 31.522879 Hu antigen C (Huc)
    2 View Details [144..277] FFAS03 5.26 No description for 2cjkA was found.
    3 View Details [278..424] PSI-BLAST 47.0 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    4 View Details [425..634] PSI-BLAST 5.39794 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.44

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle