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Protein Overview: Aats-gln-PA

General Information:
Name(s) found: Aats-gln-PA / FBpp0084240 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Glutaminyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-gln (CG10506, FBgn0027090). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21088988..21091443. It has the cytological map location 96C8. There is experimental evidence that it has the molecular function</span>: SUMO binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: glutaminyl-tRNA aminoacylation. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: glutaminyl-tRNA aminoacylation [ISS]
    Molecular Function: ATP binding [IEA][NAS]
    SUMO binding [IPI]
    glutamine-tRNA ligase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGDDLIAKF QALGMSEQKA KETLKNANVT KNLQLSLAAA GSATLSDGTG MLIYHMATKL  60
   61 KPQTADHLPL LVRYIVEHKL DNTQRVDAAL EYLLKCGQSL NANIDLQALE KECGVGVVVT 120
  121 PEQIERTVQA KIKASYKEAL LEQRYHFNSF KILQDVRGEL KWADAKSVKA AIDVEIFDLL 180
  181 GPKTEADLKP QTKANDKPKA AKPKAEVTPA AQTAEAASDG ATTISELMKT KVHFHAPGEN 240
  241 FKADGYVVTE HTERLLKEHL ARTGGKVHTR FPPEPNGILH IGHAKAININ FGYAAAHDGV 300
  301 CYLRYDDTNP EKEEEKFFLA IKEMVEWLGY KPFKITYSSD NFQQLYEWAV VLINKGLAYV 360
  361 CHQKAEELKG FNPKPSPWRE RPIEESLRLF EDMKRGKIDE GAATLRMKVT LEEGKMDPVA 420
  421 YRIKFISHHR TGSDWCIYPT YDYTHCLCDS LEDITHSLCT KEFQSRRSSY YWLCNALGIY 480
  481 CPVQWEYGRL NMNYALVSKR KIAKLITEQI VHDWDDPRLF TLTALRRRGF PAEAINNFCA 540
  541 QMGVTGAQIA VDPAMLEAAV RDVLNVTAPR RLVVLEPLKV TIKNFPHAAP VQLEVPDFPQ 600
  601 NPQQGTHKIT LDKVIYIEQG DFKLEPEKGY RRLAPKQSVG LRHAGLVISV DEIVKDPATG 660
  661 QVVELICTSQ PAEQAEKPKA FVQWVSQPIQ LEVRLYEQLF KHKNPEDPNE VPGGFLSDIS 720
  721 EQSMSVVVAF ADRALNQAKV YDKFQFERIG FFSVDPDTSA NHLVFNRTVG LKEDAGKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] Pfam 92.657577 No description for PF04558.6 was found. No confident structure predictions are available.
    2 View Details [148..249] PSI-BLAST 14.0 Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
    3 View Details [250..778] PSI-BLAST 171.0 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • glutamine-tRNA ligase activity
    		•  7.66556935228325 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  4.64665624411373 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.61484562096458 bayes_pls_golite062009
  • structural molecule activity
    		•  4.261982318682 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • 5S rRNA binding
    		•  2.25646775578129 bayes_pls_golite062009
  • rRNA binding
    		•  2.12571610259264 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.06535308346284 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.47302762432927 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.161799496958314 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
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