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Protein Overview: beta4GalT7-PA

General Information:
Name(s) found: beta4GalT7-PA / FBpp0084130 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Ã?&#142;Ã?²-4-galactosyltransferase 7 is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?²4GalT7 (CG11780, FBgn0039258). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20848995..20850205. It has the cytological map location 96B16. There is experimental evidence that it has the molecular function</span>: xylosylprotein 4-beta-galactosyltransferase activity; galactosyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: proteoglycan biosynthetic process. 9 alleles are reported. The phenotypes of these alleles are annotated with: eye; interommatidial bristle; wing; ommatidium; wing vein L2. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 322 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Golgi apparatus [IDA]
    Biological Process: chondroitin sulfate biosynthetic process [NAS]
    carbohydrate metabolic process [IEA]
    heparan sulfate proteoglycan biosynthetic process [NAS]
    glycosaminoglycan biosynthetic process [NAS]
    proteoglycan biosynthetic process [ISS]
    Molecular Function: metal ion binding [ISS]
    galactosyltransferase activity [IDA][NAS]
    xylosylprotein 4-beta-galactosyltransferase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNISTINWV FVCGLSFCLG GIAVLSLMPL GSDCVCPLSN PLAKLAGGGE GVSVIKKEPA  60
   61 DEKQPQPHDH GASVHKMALL VPFRDRFEEL LQFVPHMTAF LKRQGVAHHI FVLNQVDRFR 120
  121 FNRASLINVG FQFASDVYDY IAMHDVDLLP LNDNLLYEYP SSLGPLHIAG PKLHPKYHYD 180
  181 NFVGGILLVR REHFKQMNGM SNQYWGWGLE DDEFFVRIRD AGLQVTRPQN IKTGTNDTFS 240
  241 HIHNRYHRKR DTQKCFNQKE MTRKRDHKTG LDNVKYKILK VHEMLIDQVP VTILNILLDC 300
  301 DVNKTPWCDC SGTAAAASAV QT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..322] PSI-BLAST 90.69897 beta 1,4 galactosyltransferase (b4GalT1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity, transferring hexosyl groups
    		•  4.49413422196176 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  4.08451171179562 bayes_pls_golite062009
  • glucuronosyltransferase activity
    		•  4.02728111834164 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  3.4614674054855 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  3.19923094610567 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  2.61384249067286 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.60650378115696 bayes_pls_golite062009
  • heparan sulfate N-acetylglucosaminyltransferase activity
    		•  2.42139682088952 bayes_pls_golite062009
  • N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
    		•  1.98507004131156 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  1.6603302881547 bayes_pls_golite062009
  • transferase activity
    		•  1.47184463413038 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03393419806381 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.992215002450258 bayes_pls_golite062009
  • glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  0.973286130942889 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  0.82476668382543 bayes_pls_golite062009
  • binding
    		•  0.667238976803188 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.321928989676507 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.218759888732981 bayes_pls_golite062009
  • UDP-galactosyltransferase activity
    		•  0.10185872015123 bayes_pls_golite062009
  • galactosyltransferase activity
    		•  0.0931461042017721 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.0278258721775009 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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