GO TERM SUMMARY
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Name: |
heparan sulfate proteoglycan biosynthetic process |
Acc: |
GO:0015012 |
Aspect: |
Biological Process |
Desc: |
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. |
Synonyms:
- heparin proteoglycan biosynthetic process
- heparan sulfate proteoglycan formation
- heparan sulphate proteoglycan biosynthesis
- heparan sulphate proteoglycan biosynthetic process
- heparan sulfate proteoglycan synthesis
- heparan sulfate proteoglycan biosynthesis
- heparan sulfate proteoglycan anabolism
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