Protein Overview: FBpp0306892, Orc...

General Information:
Name(s) found:	FBpp0306892 [FlyBase] Orct2-PA / FBpp0083982 [FlyBase]
Description(s) found: Found 28 descriptions. SHOW ALL	type=protein; loc=3R:20099152..20100855; ID=FBpp0306892; name=Orct2-PB; parent=FBgn0086365,FBtr0334869; dbxref=FlyBase:FBpp0306892,FlyBase_Annotation_IDs:CG13610-PB,REFSEQ:NP_001262907,GB_protein:AGB96287; MD5=05916d1553f1e928636716b286950122; length=567; release=r5.56; species=Dmel; [FlyBase] The gene Organic cation transporter 2 is referred to in FlyBase by the symbol Dmel\Orct2 (CG13610, FBgn0086365). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20098753..20101013. It has the cytological map location 95F8. Based on sequence similarity, it is predicted to have molecular function</span>: organic cation transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell growth; germ-band shortening; positive regulation of multicellular organism growth. 13 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing; germ band. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	567 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA][NAS]
Biological Process:	positive regulation of cell growth [IMP] organic cation transport [ISS][NAS] transmembrane transport [IEA] germ-band shortening [IMP] positive regulation of multicellular organism growth [IMP]
Molecular Function:	organic cation transmembrane transporter activity [ISS] cation transmembrane transporter activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYDEAIIHL GDFGRYQKII YFLICLTSIP VAFHKLAGVF LLAKPDFRCA LPFENGSSYD  60
   61 LPTHLWNLSY PENERCSYYD VDYTEEYLNG SIPRSSNETK TCSSYVYDRS KYLNSAVTEW 120
  121 NLVCGRDFMA ATSDSLFMLG VLLGSIVFGQ LSDKYGRKPI LFASLVIQVL FGVLAGVAPE 180
  181 YFTYTFARLM VGATTSGVFL VAYVVAMEMV GPDKRLYAGI FVMMFFSVGF MLTAVFAYFV 240
  241 HDWRWLQIAL TLPGLIFMFY YWIIPESARW LLLKGRKDCA IANMQKAARF NKVEISDEAL 300
  301 SELLDEGENS EEKAKQKLED QELDEGPPPS VWDLFCYPNL RRKTLLIFLD WLVTSGVYYG 360
  361 LSWNTSNLGG NVLLNFVISG AVEIPAYIFL LLTLNRWGRR SILCGCLVMA GLSLLATVII 420
  421 PQRMHTLIVA CAMLGKLAIT ASYGTVYIFS AEQFPTVVRN VALGAASMVA RISGMMAPFL 480
  481 NFLATIWKPL PLLICGSLTL VAGLLSLLLP ETHNKPMLET IADGERFGKK TKADVYLETG 540
  541 QELRAPEAQP LKGSGETNGS TIANGHK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	5.46247398538901	bayes_pls_golite062009
ion transmembrane transporter activity	4.58978526526921	bayes_pls_golite062009
cation transmembrane transporter activity	4.31967711223954	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
anion transmembrane transporter activity	3.94605227012838	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
organic anion transmembrane transporter activity	3.3413526350788	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	2.52916479889426	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	2.39244854801368	bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity	2.39244854801368	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
binding	1.46605775041083	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
phosphate transmembrane transporter activity	0.312628600969375	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..567]	PSI-BLAST	29.221849	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

Protein Overview: FBpp0306892, Orc...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: