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Protein Overview: Aats-glupro-PA

General Information:
Name(s) found: Aats-glupro-PA / FBpp0083898 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Glutamyl-prolyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-glupro (CG5394, FBgn0005674). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19777852..19784117. It has the cytological map location 95D1. There is experimental evidence that it has the molecular function</span>: SUMO binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: prolyl-tRNA aminoacylation; glutamyl-tRNA aminoacylation. 8 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1714 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    aminoacyl-tRNA synthetase multienzyme complex [NAS]
    Biological Process: glutamyl-tRNA aminoacylation [ISS]
    prolyl-tRNA aminoacylation [ISS]
    Molecular Function: ATP binding [IEA]
    SUMO binding [IPI]
    proline-tRNA ligase activity [ISS][NAS]
    glutamate-tRNA ligase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKLKANLN NPPISGLATA HLINGTVPVE IVWSKEETSL QFPDNRLLVC HSNNDVLRAL  60
   61 ARAAPDYKLY GETAIERTQI DHWLSFSLTC EDDISWALSF LDKSIAPVTY LVANKLTIAD 120
  121 FALFNEMHSR YEFLAAKGIP QHVQRWYDLI TAQPLIQKVL QSLPEDAKVK RSPQSSKEQT 180
  181 PAKTGERKQE GKFVDLPGAE MGKVVVRFPP EASGYLHIGH AKAALLNQYY ALAFQGTLIM 240
  241 RFDDTNPAKE TVEFENVILG DLEQLQIKPD VFTHTSNYFD LMLDYCVRLI KESKAYVDDT 300
  301 PPEQMKLERE QRVESANRSN SVEKNLSLWE EMVKGSEKGQ KYCVRAKIDM SSPNGCMRDP 360
  361 TIYRCKNEPH PRTGTKYKVY PTYDFACPIV DAIENVTHTL RTTEYHDRDD QFYWFIDALK 420
  421 LRKPYIWSYS RLNMTNTVLS KRKLTWFVDS GLVDGWDDPR FPTVRGIIRR GMTVEGLKEF 480
  481 IIAQGSSKSV VFMNWDKIWA FNKKVIDPIA PRYTALEKEK RVIVNVAGAK VERIQVSVHP 540
  541 KDESLGKKTV LLGPRIYIDY VDAEALKEGE NATFINWGNI LIRKVNKDAS GNITSVDAAL 600
  601 NLENKDFKKT LKLTWLAVED DPSAYPPTFC VYFDNIISKA VLGKDEDFKQ FIGHKTRDEV 660
  661 PMLGDPELKK CKKGDIIQLQ RRGFFKVDVA YAPPSGYTNV PSPIVLFSIP DGHTKDVPTS 720
  721 GLKVNAPDAK ATKKASSPVS SSGQASELDS QISQQGDLVR DLKSKKAAKD QIDVAVKKLL 780
  781 ALKADYKSAT GKDWKPGQTS ASSAPVPAAS SSSANDAVSV NASIVKQGDL VRDLKGKKAS 840
  841 KPEIDAAVKT LLELKAQYKT LTGQDWKPGT VPTTAAPSAS AAPSVGVNDS VAQILSQITA 900
  901 QGDKVRELKS AKADKATVDA AVKTLLSLKA DYKAATGSDW KPGTTAPAPA AAPVKVKQEK 960
  961 NPDPASVLTV NTLLNKIAQQ GDKIRQLKSA KSEKSLVEAE VKLLLALKTD YKSLTGQEWK1020
 1021 PGTVAPAPTT VNVIDLTGGD SGSDVGSVLS KIQAQGDKIR KLKSEKAAKN VIDPEVKTLL1080
 1081 ALKGEYKTLS GKDWTPDAKS EPAVVKKEAS PVSMASPAKD ELTQEINAQG EKVRAAKGNK1140
 1141 AAKEVIDAEV AKLLALKAKY KEVTGTDFPV AGRGGGGGGG SAKKAPKEAQ PKPAKPVKKE1200
 1201 PAADASGAVK KQTRLGLEAT KEDNLPDWYS QVITKGEMIE YYDVSGCYIL RQWSFAIWKA1260
 1261 IKTWFDAEIT RMGVKECYFP IFVSKAVLEK EKTHIADFAP EVAWVTKSGD SDLAEPIAVR1320
 1321 PTSETVMYPA YAKWVQSYRD LPIRLNQWNN VVRWEFKQPT PFLRTREFLW QEGHTAFADK1380
 1381 EEAAKEVLDI LDLYALVYTH LLAIPVVKGR KTEKEKFAGG DYTTTVEAFI SASGRAIQGA1440
 1441 TSHHLGQNFS KMFEIVYEDP ETQQKKYVYQ NSWGITTRTI GVMIMVHADN QGLVLPPHVA1500
 1501 CIQAIVVPCG ITVNTKDDER AQLLDACKAL EKRLVGGGVR CEGDYRDNYS PGWKFNHWEL1560
 1561 KGVPLRLEVG PKDLKAQQLV AVRRDTVEKI TIPLADVEKK IPALLETIHE SMLNKAQEDM1620
 1621 TSHTKKVTNW TDFCGFLEQK NILLAPFCGE ISCEDKIKAD SARGEEAEPG APAMGAKSLC1680
 1681 IPFDQPAPIA ASDKCINPSC TNKPKFYTLF GRSY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..174] PSI-BLAST 14.221849 No description for 2hraA was found.
    2 View Details [175..714] PSI-BLAST 144.0 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
    3 View Details [715..1017] PSI-BLAST 22.221849 Heavy meromyosin subfragment
    4 View Details [1018..1514] PSI-BLAST 52.39794 No description for 2dq0A was found.
    5 View Details [1515..1648] PSI-BLAST 93.154902 Prolyl-tRNA synthetase (ProRS) domain; C-terminal domain of ProRS; Prolyl-tRNA synthetase (ProRS)
    6 View Details [1649..1714] PSI-BLAST 126.0 Prolyl-tRNA synthetase (ProRS) domain; C-terminal domain of ProRS; Prolyl-tRNA synthetase (ProRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • glutamine-tRNA ligase activity
    		•  7.66556935228325 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  5.13420185144914 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  4.64665624411373 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.61484562096458 bayes_pls_golite062009
  • structural molecule activity
    		•  4.261982318682 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • 5S rRNA binding
    		•  2.25646775578129 bayes_pls_golite062009
  • rRNA binding
    		•  2.12571610259264 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64840822019417 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • binding
    		•  1.11291710031577 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.06535308346284 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle