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Protein Overview: CG10254-PA, CG10...

General Information:
Name(s) found: CG10254-PA / FBpp0083868 [FlyBase]
CG10254-PB / FBpp0083867 [FlyBase]
Description(s) found:
Found 33 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG10254 (CG10254, FBgn0027512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19514727..19520705. It has the cytological map location 95A7. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification; regulation of protein metabolic process. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG10254 (CG10254, FBgn0027512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19514727..19520705. It has the cytological map location 95A7. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification; regulation of protein metabolic process. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1398 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of protein metabolic process [IEA]
    post-translational protein modification [IEA]
    Molecular Function: ubiquitin-protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSDVAGAAA PGGTPGQPQQ EQEQSLAEAA PRTPTLANPP PSSQELGRTP NQESRHNANS  60
   61 HSRRSGGGQV PSKAQGNTES QFFLEDGVFR IDRRGRVHFG LVTATTETYS SSEEEDVDSL 120
  121 SRGEVRVAFY PGGKEMVMTE QSIGLADRTL MPGDVVRRRL PGENVLAGQA GYVRDVNVRA 180
  181 DVMVMGSRMV IKNVPAERLR PISEWNQYVP LCMDTWIGTI IDINECAVLK SSNGARVEIT 240
  241 SNDFHKFKDA VSECDRTVFN PNVFFPGNIV IGRMPPPDRV KNLTPEITHP LTRKGRAVYT 300
  301 VESVETTSIN VDWSCRAIGN ATGSDDTDSD PLKEPRSLIK GEELHKVKRL SLYESYELQI 360
  361 HDRFYLKYSK CDLLVKYADW ENEQAEKYIP IFHAQKKMQR KASKLNASAS TSGNARSVPK 420
  421 FRRMPNKISG MRLPRPPSDQ THNACKSSKR SKEDVLTSED EDEFEEFMQP LDQSMTAEKE 480
  481 VEVAEDALPP SAATTAAAGV EVQAPRITMR SAKRRQVKKK IRSVKKTIYS PFNKKETTPK 540
  541 DGDEIVVETL VVYSSVTVVW QDGTVESGVH STQLYPIHHL DNHEFFPGDF VTKANDISTG 600
  601 ATDYGVIQCV DHDARIAKVM WFNIYTNIDN PIPLFKGLEE LSVYDMKDHT DYQYRPGTVV 660
  661 IRVSNFTGED VNSTAGQVID NYPNGRVRVW WAKGHITLCY PQDLFQPFEQ DEQNEQDQDV 720
  721 YGSDGSEDSW ETESENSHIS SSDNDDDILT GIDRATEAMK VLEKMFRVLH PNRKAEVLYD 780
  781 LLDVYKNCRA LDRLLNTKFF DEFNFKGIVR CKPITSKVCS DSATHERATP ETPETSAAVP 840
  841 KESSTLQAEL EPVLMDPSVQ SSSSPTKRKS STEMDEVLCK KSTDEISEEQ DYQVEVVEVI 900
  901 EDPPLVREYR CKYNEMFANA RRSIAKAIEN RTKNDSGVHS RGEITSDESN NHPDSENKLD 960
  961 IKHPTINVMD DLEIELVASG DADVCEVFCY LIKFQMARIR KTVAVTLGKT NDNPKQEKED1020
 1021 VSDAEEAIEA VSQEAELAND GATECNTMAE DEAMEEPLNL NALSESLPAI DQTGPMACSS1080
 1081 PSWSIIPDTP SVDENCFQVL PNAPAAHNFI SNLITPANKA QYQRAVQREY LMLKSSLPNG1140
 1141 VVVRAYEDRM DLMSVMMVGP KRTPYQNALF FFDFQFGRDY PKSPPVCHYI SYCTDRLNPN1200
 1201 LYEGGRVCVS LLGTWMGRDN EVWSPSSTML QVLVSIQGLI LVDEPYYNEA GYEKQRGTQL1260
 1261 GNENSRVYNE MAIIKIAQST VKQLTNPPLI FRNELIEHFK EFGTELYARM RAWSEYSLEA1320
 1321 QRQNITKIKD MPVEYKASCE LPEFPLLPCS RGFCIAVKRV LSQLQSELTA LGANLVTDER1380
 1381 NGIATGIGTA PRAAPEEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] deduced N/A No confident structure predictions are available.
    2 View Details [131..346] deduced N/A No confident structure predictions are available.
    3 View Details [347..488] deduced N/A No confident structure predictions are available.
    4 View Details [489..601] MSA 1.025989 View MSA. No confident structure predictions are available.
    5 View Details [602..862] deduced N/A No confident structure predictions are available.
    6 View Details [863..1116] deduced N/A No confident structure predictions are available.
    7 View Details [1117..1322] PSI-BLAST 37.221849 No description for 2pwqA was found.
    8 View Details [1323..1398] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle