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Protein Overview: cdc16-PA

General Information:
Name(s) found: cdc16-PA / FBpp0083769 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene cdc16 is referred to in FlyBase by the symbol Dmel\cdc16 (CG6759, FBgn0025781). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19106955..19109845. It has the cytological map location 94E9. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of mitotic metaphase/anaphase transition; cell cycle. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 718 amino acids

    Gene Ontology:
    Cellular Component: anaphase-promoting complex [ISS][NAS]
    Biological Process: regulation of mitotic metaphase/anaphase transition [IMP]
    mitotic anaphase [NAS]
    cell cycle [IMP]
    Molecular Function: ubiquitin-protein ligase activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGDTENTST DTTNEHIDLA LYRQLVKQFI DMRRYSTALF WAEKVAVLGG LEPRDIYYQA  60
   61 QCMYLLGEYH RAAHTIQHHK LEKNSLPCFN LLLESLYAAK EFTEAANVIQ NVEVEVMTTS 120
  121 LINQPVDASS GCYLESNSVF GGEENHRNEL LSSIYLMKGK VYEALDNRGM AMDFYVQALH 180
  181 KSIYCFEALE ALVQHEMLMA WEEFELMHHL PLAQQSSEAD AKFILKLYES RLKKYYELIS 240
  241 ARNAEEMSPI VNPDILQFIK EFTARVQQSG SSDTQMPKVS AVKVPLTPSQ FMSPAQKVLE 300
  301 DLKAPTFSLQ TSLSKASSLI DASHRSMFDS SSRRRSRDHD TDTLIPIAEC LDRVQRSTDL 360
  361 MAAEAEKCFY DCDYKQCLKI LNELLKVDPF HNTALTIQIA CLVENGDFNR LFYVAHKLVD 420
  421 RYPDKAISWY AVGCYYDMIG KSDPARRYLS KATALDRLYG PAWLAYGHSF ANENEHEQAM 480
  481 AAYFKATQLM RGCHLPLLYI GVECGLTKNL ELAEKFFLQA MNIAPLDVYV LHELGVIKYE 540
  541 YEFFDGAATI FQCTVDIVKQ RAKSNNEEIS SRWEPLFINL GHSLRKVHKY EEALYNFQYA 600
  601 LLLKPQSPTT YTSIGFIHAL LGNLDPAIEA FHKSLALNRD CIVTSTILKS CIEDLMDDSA 660
  661 TIDEICSAAL RDVAKNITAN SRRVLNSDKF NGMKLKFDEE EEFANSDSNM VVEMSFDT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..525] PSI-BLAST 31.30103 No description for 2gw1A was found.
    2 View Details [526..571] PSI-BLAST 4.154902 Clathrin heavy chain proximal leg segment
    3 View Details [572..718] PSI-BLAST 67.69897 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle