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View Structure Prediction Details

Protein: cdc16-PA
Organism: Drosophila melanogaster
Length: 718 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc16-PA.

Description E-value Query
Range
Subject
Range
gi|73670079, gi|... - gi|73670079|ref|YP_306094.1| TPR repeat-containing protein [Methanosarcina barkeri str. Fusaro], gi|...
452.0 [0..2] [716..94]

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Predicted Domain #1
Region A:
Residues: [1-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGDTENTST DTTNEHIDLA LYRQLVKQFI DMRRYSTALF WAEKVAVLGG LEPRDIYYQA  60
   61 QCMYLLGEYH RAAHTIQHHK LEKNSLPCFN LLLESLYAAK EFTEAANVIQ NVEVEVMTTS 120
  121 LINQPVDASS GCYLESNSVF GGEENHRNEL LSSIYLMKGK VYEALDNRGM AMDFYVQALH 180
  181 KSIYCFEALE ALVQHEMLMA WEEFELMHHL PLAQQSSEAD AKFILKLYES RLKKYYELIS 240
  241 ARNAEEMSPI VNPDILQFIK EFTARVQQSG SSDTQMPKVS AVKVPLTPSQ FMSPAQKVLE 300
  301 DLKAPTFSLQ TSLSKASSLI DASHRSMFDS SSRRRSRDHD TDTLIPIAEC LDRVQRSTDL 360
  361 MAAEAEKCFY DCDYKQCLKI LNELLKVDPF HNTALTIQIA CLVENGDFNR LFYVAHKLVD 420
  421 RYPDKAISWY AVGCYYDMIG KSDPARRYLS KATALDRLYG PAWLAYGHSF ANENEHEQAM 480
  481 AAYFKATQLM RGCHLPLLYI GVECGLTKNL ELAEKFFLQA MNIAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.30103
Match: 2gw1A
Description: No description for 2gw1A was found.

Predicted Domain #2
Region A:
Residues: [526-571]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDVYVLHELG VIKYEYEFFD GAATIFQCTV DIVKQRAKSN NEEISS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1b89A
Description: Clathrin heavy chain proximal leg segment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [572-718]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RWEPLFINLG HSLRKVHKYE EALYNFQYAL LLKPQSPTTY TSIGFIHALL GNLDPAIEAF  60
   61 HKSLALNRDC IVTSTILKSC IEDLMDDSAT IDEICSAALR DVAKNITANS RRVLNSDKFN 120
  121 GMKLKFDEEE EFANSDSNMV VEMSFDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.69897
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle