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Protein Overview: ND42-PB, FBpp030...

General Information:
Name(s) found: FBpp0307181 [FlyBase]
ND42-PB / FBpp0083571 [FlyBase]
ND42-PA / FBpp0083570 [FlyBase]
Description(s) found:
Found 45 descriptions.
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  • type=protein; loc=3R:join(17853743..17854870,17854938..17855033); ID=FBpp0307181; name=ND42-PC; parent=FBgn0019957,FBtr0335194; dbxref=REFSEQ:NP_001262821,GB_protein:AGB96201,FlyBase:FBpp0307181,FlyBase_Annotation_IDs:CG6343-PC; MD5=4f491c76bbd99b4861d6e1236cf38e76; length=407; release=r5.56; species=Dmel; [FlyBase]
  • The gene NADH:ubiquinone reductase 42kD subunit precursor is referred to in FlyBase by the symbol Dmel\ND42 (CG6343, FBgn0019957). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17853427..17855115. It has the cytological map location 94A1. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene NADH:ubiquinone reductase 42kD subunit precursor is referred to in FlyBase by the symbol Dmel\ND42 (CG6343, FBgn0019957). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17853427..17855115. It has the cytological map location 94A1. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    mitochondrial respiratory chain complex I [ISS][NAS]
    mitochondrial matrix [NAS]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
    Molecular Function: ATP binding [IEA]
    NADH dehydrogenase activity [ISS][NAS]
    NADH dehydrogenase (ubiquinone) activity [NAS]
    phosphotransferase activity, alcohol group as acceptor [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAVFRVGLV RLVSRATQSP NLLQAQTNAL PAAFQQRCSI SGKTMRGGPR VPKAAPYPYK  60
   61 TKKYSVFNAI FDKTSKRFDE NSKVICVEGP IAAGKSKFAK ELAEELDMEY YPAVDLDLIY 120
  121 INSYGYDMRK LDPQLPPSCR SYDVRNFCLD PSHDLAAQFQ IRMYMLRYSQ YIDALQHVLS 180
  181 TGQGVVLERS PYSDFVFMEA MFRQGYLSRG ARSVYNELRQ NTIGELLKPH LVIYLDLPVD 240
  241 AVKKQIKARN VDYEVQSKVF SDAYLSDLEQ LYKQQYLKDI STHAELLIYD WTAGGETEVV 300
  301 VEDIERIDFN QFEADIHNKK MLDWRFPLEA EWCEARIKYC HEKPDLMNYF NVPRFDVPEL 360
  361 VRSADDGKVW RDVWFNAPGM KYRPGYNADM GDEGLLTKTK IGINQGI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..311] PSI-BLAST 40.39794 Deoxycytidine kinase
    2 View Details [312..407] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.59240819084968 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.32597131015894 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.27130158388246 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.20563367652813 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.1945674591238 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.16363151312976 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.06875573889397 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.97411320405542 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.90050421101998 bayes_pls_golite062009
  • binding
    		•  1.662143711113 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.53142082854758 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.52938239070386 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.52887308780164 bayes_pls_golite062009
  • nucleotide binding
    		•  1.52746968836881 bayes_pls_golite062009
  • ATP binding
    		•  1.23942044024113 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.21044170258803 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.19481945569892 bayes_pls_golite062009
  • electron carrier activity
    		•  1.01221075506867 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • kinase activity
    		•  0.641541011250583 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.546796591575762 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.543610140926125 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.540750418412449 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.517457589081898 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.40876498215632 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  0.38711726712063 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  0.160596246929241 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0646123847220056 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle