Protein Overview: slou-PA

General Information:
Name(s) found:	slou-PA / FBpp0083521 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|8531\|emb\|CAA39067.1\| S59 protein [Drosophila melanogaster] [NCBI NR] gi\|23171898\|gb\|AAF55901.3\| slouch [Drosophila melanogaster] [NCBI NR] gi\|17136362\|ref\|NP_476657.1\| slouch [Drosophila melanogaster] [NCBI NR] gi\|123395\|sp\|P22807.1\|SLOU_DROME RecName: Full=Homeobox protein slou; AltName: Full=S59/2; AltName: Full=Protein slouch; AltName: Full=Homeobox protein NK-1 [NCBI NR] pir\|\|A36664 S59/2 homeotic protein - fruit fly (Drosophila melanogaster) [NCBI NR] Homeobox protein slou OS=Drosophila melanogaster GN=slou PE=2 SV=1 [Swiss-Prot] (P22807) Homeobox protein slou (S59/2) (Slouch protein) (Homeobox protein NK-1) [Swiss-Prot] The gene slouch is referred to in FlyBase by the symbol Dmel\slou (CG6534, FBgn0002941). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17374375..17383004. It has the cytological map location 93E4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: muscle cell fate determination. 5 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; abdominal transverse muscle; abdominal oblique muscle; adult abdominal myoblast; larval abdominal segment 5; acute muscle; adult; abdominal ventral acute muscle 2; adult segment. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG6534-PA translation from_gene[CG6534 slou FBgn0002941] seq_release:3 mol_weight=69956 cds_boundaries:(3R:17,365,716..17,373,544[-]) aa_length:659 transcript_info:[CG6534-RA seq_release:3] gene_info:[gene symbol:slou FBgn0002941 gene_boundaries:(3R:1 [hmr_yeast5_DM3-1_pombe.fasta] CG6534-PA [Drosophila melanogaster]gi\|17136362\|ref\|NP_476657.1\| CG6534-PA [Drosophila melanogaster]gi\|103363\|pir\|\|A36664 S59/2 homeotic protein - fruit fly (Drosophila melanogaster)gi\|8531\|emb\|CAA39067.1\| S59 protein [Drosophila melanogaster]gi\|123395 [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(17374749..17374964,17375184..17375461,17380254..17380512,17381354..17382580); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,R [fly-100309-contam.fasta] slouch CG6534-PA [Drosophila melanogaster] [nr-271106-contam.fasta] S59 protein [Drosophila melanogaster] [nr-271106-contam.fasta] CG6534-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Homeobox protein slou (S59/2) (Protein slouch) (Homeobox protein NK-1) [nr-271106-contam.fasta] type=protein; loc=3R:complement(17374749..17374964,17375184..17375461,17380254..17380512,17381354..17382580); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:complement(17374749..17374964,17375184..17375461,17380254..17380512,17381354..17382580); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3R:complement(17374749..17374964,17375184..17375461,17380254..17380512,17381354..17382580); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901,FlyMine:FBpp0083521,modMine:FBpp0083521; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(join(21555632..21556858,21554532..21554790,21549462..21549739,21549027..21549242)); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901,FlyMine:FBpp0083521,modMine:FBpp0083521; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(21555632..21556858,21554532..21554790,21549462..21549739,21549027..21549242)); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901,FlyMine:FBpp0083521,modMine:FBpp0083521; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0083521 type=protein; loc=3R:complement(join(21555632..21556858,21554532..21554790,21549462..21549739,21549027..21549242)); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901,FlyMine:FBpp0083521,modMine:FBpp0083521; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:complement(join(21555632..21556858,21554532..21554790,21549462..21549739,21549027..21549242)); ID=FBpp0083521; name=slou-PA; parent=FBgn0002941,FBtr0084123; dbxref=FlyBase:FBpp0083521,FlyBase_Annotation_IDs:CG6534-PA,GB_protein:AAF55901.3,REFSEQ:NP_476657,GB_protein:AAF55901,UniProt/Swiss-Prot:P22807,FlyMine:FBpp0083521,modMine:FBpp0083521; MD5=ce66f919f9f130604a432032fc29dba2; length=659; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	659 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS][NAS]
Biological Process:	muscle organ development [TAS] nervous system development [NAS] muscle cell fate determination [IEP] regulation of transcription, DNA-dependent [IEA][ISS] regulation of transcription [IEA] somatic muscle development [NAS] mesodermal cell fate specification [NAS]
Molecular Function:	transcription factor activity [ISS] RNA polymerase II transcription factor activity [NAS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMLQSPAQK ASDSASAQNT AVGGLMSPNS NPDSPKSNTS PDVASADSVV SGTGGGSTPP  60
   61 AAKIPKFIIS ANGAAVAGKQ EQELRYSLER LKQMSSESGS LLSRLSPLQE DSQDKEKPNH 120
  121 NNNNSLTNHN ANSNTRRSQS PPASVGSVSF SSPAQQRKLL ELNAVRHLAR PEPLQHPHAA 180
  181 LLQQHPHLLQ NPQFLAAAQQ HMHHHQHQHH QHPAHPHSHQ HPHPHPHPHP HPHPSAVFHL 240
  241 RAPSSSSTAP PSPATSPLSP PTSPAMHSDQ QMSPPIAPPQ NPPHSSQPPQ QQQVAAPSDM 300
  301 DLERIKLVAA VAARTTQASS TSALASASNS VSNASISISN SSSGSPSGRD LSDYGFRIQL 360
  361 GGLAAAAAAA AATSRQIAAA TYARSDTSEE LNVDGNDEDS NDGSHSTPSV CPVDLTRSVN 420
  421 SSAAANPSSA STSASSDRDA ATKRLAFSVE NILDPNKFTG NKLPSGPFGH PRQWSYERDE 480
  481 EMQERLDDDQ SEDMSAQDLN DMDQDDMCDD GSDIDDPSSE TDSKKGGSRN GDGKSGGGGG 540
  541 GGSKPRRART AFTYEQLVSL ENKFKTTRYL SVCERLNLAL SLSLTETQVK IWFQNRRTKW 600
  601 KKQNPGMDVN SPTIPPPGGG SFGPGAYASG LLYSHAVPYP PYGPYFHPLG AHHLSHSHS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..122]	MSA	3.196992	View MSA. No confident structure predictions are available.
2	View Details	[123..340]	MSA	3.211997	View MSA. No confident structure predictions are available.
3	View Details	[341..545]	deduced	N/A	No confident structure predictions are available.
4	View Details	[546..659]	PSI-BLAST	22.221849	DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: slou-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: