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Protein Overview: mod(mdg4)-PT

General Information:
Name(s) found: mod(mdg4)-PT / FBpp0083478 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene modifier of mdg4 is referred to in FlyBase by the symbol Dmel\mod(mdg4) (CG32491, FBgn0002781). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17177331..17203121. It has the cytological map location 93D7-93D9. There is experimental evidence that it has the molecular function</span>: protein binding; chromatin binding; SUMO binding. There is experimental evidence that it is involved in the biological process</span>: regulation of apoptosis; male meiosis I; induction of apoptosis; male meiosis chromosome segregation; oogenesis; germ cell migration; regulation of chromatin assembly or disassembly. 62 alleles are reported. The phenotypes of these alleles are annotated with: eye; ovariole; terminal filament; ovary; wing; embryo. It has 29 annotated transcripts and 29 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 610 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    polytene chromosome [IDA]
    nucleolus [IDA]
    chromatin [IMP]
    plasma membrane [ISS]
    condensed nuclear chromosome [IDA]
    Biological Process: male meiosis chromosome segregation [IMP]
    oogenesis [IMP]
    induction of apoptosis [IMP][TAS]
    male meiosis I [IMP]
    regulation of apoptosis [IMP]
    germ cell migration [IGI][IMP]
    chromatin organization [NAS]
    nucleus organization [TAS]
    regulation of chromatin assembly or disassembly [IMP]
    Molecular Function: phosphatidate phosphatase activity [ISS]
    SUMO binding [IPI]
    protein binding [IPI]
    RNA polymerase II transcription factor activity [NAS]
    chromatin binding [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADDEQFSLC WNNFNTNLSA GFHESLCRGD LVDVSLAAEG QIVKAHRLVL SVCSPFFRKM  60
   61 FTQMPSNTHA IVFLNNVSHS ALKDLIQFMY CGEVNVKQDA LPAFISTAES LQIKGLTDND 120
  121 PAPQPPQESS PPPAAPHVQQ QQIPAQRVQR QQPRASARYK IETVDDGLGD EKQSTTQIVI 180
  181 QTTAAPQATI VQQQQPQQAA QQIQSQQLQT GTTTTATLVS TNKRSAQRSS LTPASSSAGV 240
  241 KRSKTSTSAN VMDPLDSTTE TGATTTAQLV PQQITVQTSV VSAAEAKLHQ QSPQQVRQEE 300
  301 AEYIDLPMEL PTKSEPDYSE DHGDAAGDAE GTYVEDDTYG DMRYDDSYFT ENEDAGNQTA 360
  361 ANTSGGGVTA TTSKAVVKQQ SQNYSESSFV DTSGDQGNTE AQAATSASAT KIPPRKRGRP 420
  421 KTKVEDQTPK PKLLEKLQAA TLNEEASEPA VYASTTKGGV KLIFNGHLFK FSFRKADYSV 480
  481 FQCCYREHGE ECKVRVVCDQ KRVFPYEGEH VHFMQASDKS CLPSQFMPGE SGVISSLSPS 540
  541 KELLMKNTTK LEEADDKEDE DFEEFEIQEI DEIELDEPEK TPAKEEEVDP NDFREKIKRR 600
  601 LQKALQNKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] PSI-BLAST 28.221849 No description for 2nn2A was found.
    2 View Details [192..316] deduced N/A No confident structure predictions are available.
    3 View Details [317..529] PSI-BLAST 11.09691 No description for 2i13A was found.
    4 View Details [530..610] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle