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Protein Overview: rtet-PA

General Information:
Name(s) found: rtet-PA / FBpp0083412 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene tetracycline resistance is referred to in FlyBase by the symbol Dmel\rtet (CG5760, FBgn0028468). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16934170..16936554. It has the cytological map location 93B12. Based on sequence similarity, it is predicted to have molecular function</span>: sugar transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: oogenesis. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 477 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    oogenesis [IMP]
    Molecular Function: sugar transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLRSRHNG TAAMEKQSHS QTGSHHHNNN KALDKEASEN GKPEKSDPMI YIIFVSLLFD  60
   61 LLAFTIILPL LPSLLEHYRQ NDSSGLYAVL TDRVRWFQQL LGAPDRYISV LFGGFLGSMF 120
  121 SFLQFVASPI VGGLSDYYGR KPVLLACASG IALSYLIWAC SSNFALFVLA RFVGGISKGN 180
  181 ISLCMSVITD VSSVKTRGRG MALVGVAFSL GFIVGPMIGA LFAIFSDKSG STWFVLPSLL 240
  241 AFGLAVGDLV VLACCLRETL PKEKRVKEIS SALSYGLQLL NFSAIFRFAA IKNVPKKDIA 300
  301 ALRSIGLVYF LYLFLYSGLE FTVTFLMYHK FGYTSMDQAK MFLTTGVIMT LLQGSVVRRL 360
  361 PEAKIKGYAI FSLYLIVPAF VVVGLAEGSR MLYAGMTLFA ISTAFAVTCL TTLVSKYGND 420
  421 DQKGSVLGIF RSLGALARAL GPVVGCIAFW CVGSRITYIA GGLLLIYPAM ALQRARI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..477] PSI-BLAST 32.39794 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • binding
    		•  0.805286077372817 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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