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View Structure Prediction Details

Protein: rtet-PA
Organism: Drosophila melanogaster
Length: 477 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rtet-PA.

Description E-value Query
Range
Subject
Range
gi|60467752, gi|... - gi|60467752|gb|EAL65769.1| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi|29500764|g...
gi|60467752, gi|... - gi|66810832|ref|XP_639123.1| major facilitator superfamily transporter [Dictyostelium discoideum AX4...
239.0 [0..71] [450..597]

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Predicted Domain #1
Region A:
Residues: [1-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLRSRHNG TAAMEKQSHS QTGSHHHNNN KALDKEASEN GKPEKSDPMI YIIFVSLLFD  60
   61 LLAFTIILPL LPSLLEHYRQ NDSSGLYAVL TDRVRWFQQL LGAPDRYISV LFGGFLGSMF 120
  121 SFLQFVASPI VGGLSDYYGR KPVLLACASG IALSYLIWAC SSNFALFVLA RFVGGISKGN 180
  181 ISLCMSVITD VSSVKTRGRG MALVGVAFSL GFIVGPMIGA LFAIFSDKSG STWFVLPSLL 240
  241 AFGLAVGDLV VLACCLRETL PKEKRVKEIS SALSYGLQLL NFSAIFRFAA IKNVPKKDIA 300
  301 ALRSIGLVYF LYLFLYSGLE FTVTFLMYHK FGYTSMDQAK MFLTTGVIMT LLQGSVVRRL 360
  361 PEAKIKGYAI FSLYLIVPAF VVVGLAEGSR MLYAGMTLFA ISTAFAVTCL TTLVSKYGND 420
  421 DQKGSVLGIF RSLGALARAL GPVVGCIAFW CVGSRITYIA GGLLLIYPAM ALQRARI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
binding 0.805286077372817 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle