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Protein Overview: bon-PA

General Information:
Name(s) found: bon-PA / FBpp0083320 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene bonus is referred to in FlyBase by the symbol Dmel\bon (CG5206, FBgn0023097). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16418881..16438262. It has the cytological map location 92F2-92F3. Based on sequence similarity, it is predicted to have molecular function</span>: transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron development. 28 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; wing margin bristle; abdominal sternite bristle; embryonic/larval tracheal system; wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1133 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: peripheral nervous system development [TAS]
    neuron development [IMP]
    dendrite morphogenesis [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IEA]
    transcription coactivator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMDLEQLKN DFLPLIAGIK QEQLDAVPTD ALPQMSTPNT ASGAPTTSSL SSSSLSLSNP  60
   61 CDSAEKRSES NSSASAKFTL FKCVYCAQLL GSNDRPKLLE CLHVACAQCV STKFSELDRS 120
  121 LPPLIHCPVC DNASQQEFIV DNQFLIEQCT AGDSGDGVGL LGLTGEGQKS SAAASIQCSS 180
  181 CSDGAVATSW CVDCSEYICD SCVQAHQRLK ITKDHTIKPK DEANNEQLAG AAGVDKLHMC 240
  241 QLHPQEKLSL FCETCDKLTC RDCQLSDHRD HKYKFAHEIA TESRQALSTL VSEINYKRFL 300
  301 LSSATKVIDD RQQLIHDKKK DLIKEITAMA VKITNTVNTR GKQLIMRLNE VCDSKLKVLV 360
  361 EKKETLQLLS DNTDHCIDFM QNALEKGSDF AILSSKKSLV RHLQKLKCQR ADIPNPEIPV 420
  421 RIQVQLNQVS DLQKVISQLG IIIVDGKPYP PTPSPNGTPQ PQHPPRQPPS PNMAPPLRPG 480
  481 LPPGMPAGLS PNGPPVNFGP QNGPPLYSNA AQQQFNNLSM SRSFPGDGSG KVRFGGMPPV 540
  541 GMQRHGQPHV SSSTHPQNMD ISLRGLLNNQ AAQSPNAHMA FNGPPSYPGG PQGAPAPAHQ 600
  601 PMGPQMRPHF MPGQQGFSQG GGPGGGPRDA NFMNSNARFQ SQYQRMANHA QQAAAAAAMA 660
  661 GAAGGGGGQI PSPGALQRPQ MMSNPMQNVS AMQNSLGFHG SQAGFNTGPP QTSPQLGGGG 720
  721 MHSLAKWHIP QSAQQSNMCS QQGPLLPFAN GRQTSENFKI SLKSPNTLKN STPPSLGGGG 780
  781 AGHQGHGNGS SSAQLNAAAL GLGPAVSILS NVTSTNPKTP SPSTHENTKD FTEPIDKVRD 840
  841 DSINDLIATI AKLDSNGVQV LPEGRTKTTS PQVHSSTDLS NTQEVNNKNE QKDDPNEDWC 900
  901 AVCLDGGELM CCDKCPKVFH QNCHIPAISS LPDESESWQC LLCVNIKELT KTEGSEKSSS 960
  961 GELSALELRI LQRICLELYC QYEQSLNFRE PESPANTSYY EIVSSPMSLD VIRTRLDPSS1020
 1021 PNHYKDIAGF VSDVRLIFSN TYLFYQEDTK TYSNAKYLEN FFEEQLAKWL PQFEGTKPQG1080
 1081 KRNTSNSPAL LGVNATGSPS PIENGRKSCG SASLGDSDGA CLPAKRARRS AHE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] PSI-BLAST 14.0 RAG1 DIMERIZATION DOMAIN
    2 View Details [230..284] PSI-BLAST 9.0 No description for 2djaA was found.
    3 View Details [285..410] FFAS03 1.02 Fibrinogen
    4 View Details [411..962] PSI-BLAST 25.69897 No description for 1y0fA was found.
    5 View Details [963..1133] PSI-BLAST 34.30103 No description for 2f6jA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.63922952361775 bayes_pls_golite062009
  • protein binding
    		•  1.62051249360163 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.723281698537249 bayes_pls_golite062009
  • chromatin binding
    		•  0.69891726987238 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.547944704024543 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.34266089851206 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.304766790522223 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.38976505793668 bayes_pls_golite062009
  • protein binding
    		•  1.34352784773612 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.88419224843535 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle