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Protein Overview: CG4462-PA

General Information:
Name(s) found: CG4462-PA / FBpp0083259 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4462 (CG4462, FBgn0038752). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15747466..15749660. It has the cytological map location 92B7-92B8. Based on sequence similarity, it is predicted to have molecular function</span>: secondary active organic cation transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 573 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: transmembrane transport [IEA]
    Molecular Function: secondary active organic cation transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNPSPARGG ESTAPHILPN EMENDVDKRI ATPPPAPAGS DVIADVVGDF GIWQLRTILI  60
   61 IFLCKIPAAW FMACIIFTGP ELYPGSEFTC DTSYLTSSSN SSFSISDNQC YVLDESTGTS 120
  121 SECEQFNYVS SFDSLIMQFN LVCLRDIFVA WTQYWHLFGV LVGGVMGTKM MLGISPRSTY 180
  181 CVGAVAQILC GVVTGYARDF SLHCAFRCLS AVCCAIMFTA GQAIFADITA GMHRIGAIIL 240
  241 YDTFWSIGVI LLPGLSSFFN SWSLIYVGIT FPTIMLILLL YWTPDSPRWL LRHAADRFSI 300
  301 DNVEQILREG AAINDRSFKI PPDFRQQLEQ LSERLKAQPP PAPWTELWKG KRAKTHMVAA 360
  361 HLALAFFVIN FMGMLLNIRS FGRDYLVPNT IAMGFSEIIG CFLALHFTLK HNKWKWQCAG 420
  421 VFNILAGILG CMGWIFTNAD SMDADLKVSL WMIIATIPKA AVSCAQSMIL ACMNELMPAN 480
  481 KKQLFVFSVV TWARVWLLSA PFFNVLRKID TAMSLTSYCV FSILGGICTS LLLTPRLSVS 540
  541 PVVPHLEQRN TKEQSPLNAP VWTVESDVNN TRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] deduced N/A No confident structure predictions are available.
    2 View Details [104..573] PSI-BLAST 26.0 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.25550149366993 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  1.24023641504332 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle