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Protein Overview: gi|24648048, gi|...

General Information:
Name(s) found: gi|7300435 [NCBI NR]
gi|24648048 [NCBI NR]
Description(s) found:
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  • gi|7300435|gb|AAF55592.1| Mekk1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24648048|ref|NP_650750.2| Mekk1, isoform A [Drosophila melanogaster] [NCBI NR]
  • >CG7717-PA translation from_gene[CG7717 Mekk1 FBgn0024329] seq_release:3 mol_weight=181918 cds_boundaries:(3R:14,559,020..14,568,975[-]) aa_length:1612 transcript_info:[CG7717-RA seq_release:3] gene_info:[gene symbol:Mekk1 FBgn0024329 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VE37) CG7717 protein [DrosMelano7227.FASTAC.txt]
  • (AE003723) CG7717 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG7717-PA, isoform A [Drosophila melanogaster]gi|24648048|ref|NP_650750.2| CG7717-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(14559000..14559086,14559151..14559330,14559476..14562191,14562252..14562765,14562829..14563610,14564120..14564320,14565019..14565058,14565417..14565499,14568723..14568958); ID=FBpp0083098; name=Mekk1-PA; parent=FBgn0024329, [fly-100309-contam.fasta]
  • CG7717-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Mekk1 CG7717-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(14559000..14559086,14559151..14559330,14559476..14562191,14562252..14562765,14562829..14563610,14564120..14564320,14565019..14565058,14565417..14565499,14568723..14568958); ID=FBpp0083098; name=Mekk1-PA; parent=FBgn0024329,FBtr0083683; dbxref=FlyBase:FBpp0083098,FlyBase_Annotation_IDs:CG7717-PA,GB_protein:AAF55592.1,REFSEQ:NP_650750,GB_protein:AAF55592; MD5=9be7b5709b356d0c27011bdac00cf78f; length=1612; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
    • Organism: Drosophila melanogaster
    Length: 1612 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: MAPKKK cascade [IDA]
    response to oxidative stress [IMP]
    protein amino acid phosphorylation [IDA][NAS][TAS]
    mucosal immune response [IMP]
    response to stress [IDA][IMP]
    Molecular Function: ATP binding [IEA]
    receptor signaling protein serine/threonine kinase activity [NAS]
    MAP kinase kinase kinase activity [IDA][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNRRRVRTI DYLALQQSLR LQKTPAATTN AEEQVAREEE NGNGHHSTVT AETPPTPPIP  60
   61 PIPPIRLRRE QSVEEDVASK DSIDPRRESA VAYRGSVIQP PGQSSHLIAQ EEVCKMRRKK 120
  121 VEYRVKQTPS RPVQMTRNRI GALEEDMPPE DELAAHYEAF GTTPPRTRLK IKNRDWERKQ 180
  181 KVVNVTASAD LPASVGGTPK KTRTARSRVL RRNTMDCALL NEMFVNDESK RTDKRLQSLL 240
  241 RDSEREMKNS LATTAVAAPR GNSFHETAHP LESLDQIMPL NSEAMAPIPL RIASKVVESC 300
  301 NRYRCVSSRP IGYRSSAPPL AFAAQLPAGM LRSDGRATPG LGKRKDFHET FANLIKLGSV 360
  361 DRQDAKLSQE EHTWQTELKD LIWLELQAWQ ADRTVEQQDK YLFEARQGVS DLLTHIINYK 420
  421 FQPRYRREPS LISLDSGTHS DSNSNASSPL PSKMCQGCMS LYCKDCMDHQ ELALREVEGM 480
  481 LTRLEAAEAL YPSSQAMGAL HPIYKSQSFV GRIKSMCLWY NITKQNKLKL SILGKILARL 540
  541 QDEKFSWPVC TSSYIATDSG SSSASGVEND DSAVNSMDSS KPPSMAGSAS RKGVTPCHKV 600
  601 QFMLNDATHV PGETSSSNES TSTEVSQWSS ECSHSHMRKG SMHDINIFSV EPLGTCSSNG 660
  661 TGEQSTGLYR KFIENVLKSR GLAKSLAFLH KLHNVALYKA HIALEKPGAE DFDYESDAES 720
  721 IEEDVPRLDP EISREQVVEL RTYGYWSEEA QSINLPSYIP TFVFLSGIPL QFMHEFLRMR 780
  781 LETRPVRPNP LSLEQLMKEL REGLTLALTH RERYQRHITT ALVENEAELG SYISILNHYD 840
  841 ATVRKTFELY LEYIDQLVLV AVPEGNQKSV LEKEWMFTKL ISPMIKGMHT LASQKFCGII 900
  901 SKLLRSISER LVKRTVELDQ QIDGTADTDD NEEVKWQLLT ICRETQSLLT VERERSIKVL 960
  961 FFAKTFCRDV ETTDFHREHY EHDVANQQHD FICSDVKAAF KLLQQDVLQV RNKLTAIIEG1020
 1021 VQKRCCLSNM RDLDEQDKQA VLSRTREILH QGYKFGFEYH KDVIRLFEQK IMDQKDSGAH1080
 1081 TVDLALGIIA YAKMWMHFVM ERCERGRGMR PRWASQGLEF LILACDPQIT QHLDDDEFEA1140
 1141 LKQQMDRCIS HVIGITSEPE KVAKKKASPR TRKTSSPATS RSRTPTRTPM SAGMVLNPNT1200
 1201 PPLQSPPYNK LLHPQFSLKE DVSGTSYSPV DSSDYVDTPC QRSANGELRL LVPQTPPTPA1260
 1261 SPGKSSLEST PLALRQERVR DAVNRLDMDL EDGLRERRLI GQVKSLNSSD KVHIRARSVH1320
 1321 FRWHRGIKIG QGRFGKVYTA VNNNTGELMA MKEIAIQPGE TRALKNVAEE LKILEGIKHK1380
 1381 NLVRYYGIEV HREELLIFME LCSEGTLESL VELTGNLPEA LTRRFTAQLL SGVSELHKHG1440
 1441 IVHRDIKTAN IFLVDGSNSL KLGDFGSAVK IQAHTTVPGE LQGYVGTQAY MAPEVFTKTN1500
 1501 SDGHGRAADI WSVGCVVVEM ASGKRPWAQF DSNFQIMFKV GMGEKPQAPE SLSQEGHDFI1560
 1561 DHCLQHDPKR RLTAVELLEH NFCKYGRDEC SSEQLQMQVR GSFRRNVATS SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..301] deduced N/A No confident structure predictions are available.
    2 View Details [302..450] deduced N/A No confident structure predictions are available.
    3 View Details [451..592] deduced N/A No confident structure predictions are available.
    4 View Details [593..652] deduced N/A No confident structure predictions are available.
    5 View Details [653..728] deduced N/A No confident structure predictions are available.
    6 View Details [729..917] deduced N/A No confident structure predictions are available.
    7 View Details [918..1031] deduced N/A No confident structure predictions are available.
    8 View Details [1032..1270] deduced N/A No confident structure predictions are available.
    9 View Details [1271..1612] PSI-BLAST 78.0 Catalytic and ubiqutin-associated domains of MARK2/PAR-1: Wild type


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle