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View Structure Prediction Details

Protein: gi|24648048, gi|...
Organism: Drosophila melanogaster
Length: 1612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24648048, gi|....

Description E-value Query
Range
Subject
Range
Mekk1-PB - The gene Mekk1 is referred to in FlyBase by the symbol Dmel\Mekk1 (CG7717, FBgn0024329). It is a pro...
1668.0 [0..1] [1612..1]

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Predicted Domain #1
Region A:
Residues: [1-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNRRRVRTI DYLALQQSLR LQKTPAATTN AEEQVAREEE NGNGHHSTVT AETPPTPPIP  60
   61 PIPPIRLRRE QSVEEDVASK DSIDPRRESA VAYRGSVIQP PGQSSHLIAQ EEVCKMRRKK 120
  121 VEYRVKQTPS RPVQMTRNRI GALEEDMPPE DELAAHYEAF GTTPPRTRLK IKNRDWERKQ 180
  181 KVVNVTASAD LPASVGGTPK KTRTARSRVL RRNTMDCALL NEMFVNDESK RTDKRLQSLL 240
  241 RDSEREMKNS LATTAVAAPR GNSFHETAHP LESLDQIMPL NSEAMAPIPL RIASKVVESC 300
  301 N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [302-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYRCVSSRPI GYRSSAPPLA FAAQLPAGML RSDGRATPGL GKRKDFHETF ANLIKLGSVD  60
   61 RQDAKLSQEE HTWQTELKDL IWLELQAWQA DRTVEQQDKY LFEARQGVSD LLTHIINYKF 120
  121 QPRYRREPSL ISLDSGTHSD SNSNASSPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [451-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSKMCQGCMS LYCKDCMDHQ ELALREVEGM LTRLEAAEAL YPSSQAMGAL HPIYKSQSFV  60
   61 GRIKSMCLWY NITKQNKLKL SILGKILARL QDEKFSWPVC TSSYIATDSG SSSASGVEND 120
  121 DSAVNSMDSS KPPSMAGSAS RK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [593-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVTPCHKVQF MLNDATHVPG ETSSSNESTS TEVSQWSSEC SHSHMRKGSM HDINIFSVEP  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [653-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGTCSSNGTG EQSTGLYRKF IENVLKSRGL AKSLAFLHKL HNVALYKAHI ALEKPGAEDF  60
   61 DYESDAESIE EDVPRL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [729-917]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPEISREQVV ELRTYGYWSE EAQSINLPSY IPTFVFLSGI PLQFMHEFLR MRLETRPVRP  60
   61 NPLSLEQLMK ELREGLTLAL THRERYQRHI TTALVENEAE LGSYISILNH YDATVRKTFE 120
  121 LYLEYIDQLV LVAVPEGNQK SVLEKEWMFT KLISPMIKGM HTLASQKFCG IISKLLRSIS 180
  181 ERLVKRTVE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [918-1031]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDQQIDGTAD TDDNEEVKWQ LLTICRETQS LLTVERERSI KVLFFAKTFC RDVETTDFHR  60
   61 EHYEHDVANQ QHDFICSDVK AAFKLLQQDV LQVRNKLTAI IEGVQKRCCL SNMR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1032-1270]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLDEQDKQAV LSRTREILHQ GYKFGFEYHK DVIRLFEQKI MDQKDSGAHT VDLALGIIAY  60
   61 AKMWMHFVME RCERGRGMRP RWASQGLEFL ILACDPQITQ HLDDDEFEAL KQQMDRCISH 120
  121 VIGITSEPEK VAKKKASPRT RKTSSPATSR SRTPTRTPMS AGMVLNPNTP PLQSPPYNKL 180
  181 LHPQFSLKED VSGTSYSPVD SSDYVDTPCQ RSANGELRLL VPQTPPTPAS PGKSSLEST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1271-1612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLALRQERVR DAVNRLDMDL EDGLRERRLI GQVKSLNSSD KVHIRARSVH FRWHRGIKIG  60
   61 QGRFGKVYTA VNNNTGELMA MKEIAIQPGE TRALKNVAEE LKILEGIKHK NLVRYYGIEV 120
  121 HREELLIFME LCSEGTLESL VELTGNLPEA LTRRFTAQLL SGVSELHKHG IVHRDIKTAN 180
  181 IFLVDGSNSL KLGDFGSAVK IQAHTTVPGE LQGYVGTQAY MAPEVFTKTN SDGHGRAADI 240
  241 WSVGCVVVEM ASGKRPWAQF DSNFQIMFKV GMGEKPQAPE SLSQEGHDFI DHCLQHDPKR 300
  301 RLTAVELLEH NFCKYGRDEC SSEQLQMQVR GSFRRNVATS SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.0
Match: 1zmuA
Description: Catalytic and ubiqutin-associated domains of MARK2/PAR-1: Wild type
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle