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Protein Overview: PP2A-B'-PA

General Information:
Name(s) found: PP2A-B'-PA / FBpp0082977 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene PP2A-B' is referred to in FlyBase by the symbol Dmel\PP2A-B' (CG7913, FBgn0042693). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13993451..14005771. It has the cytological map location 90F4-90F5. Based on sequence similarity, it is predicted to have molecular function</span>: protein phosphatase type 2A regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein amino acid dephosphorylation. 23 alleles are reported. The phenotype of these alleles is annotated with: salivary gland. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 951 amino acids

    Gene Ontology:
    Cellular Component: protein phosphatase type 2A complex [IEA][ISS]
    Biological Process: neuromuscular junction development [IMP]
    anti-apoptosis [NAS]
    neuromuscular synaptic transmission [IMP]
    signal transduction [IEA]
    protein amino acid dephosphorylation [ISS]
    Molecular Function: protein phosphatase type 2A regulator activity [IEA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFGAMLLTG NGLKGPKQQQ QQHQQEPQQQ QQQSQQQQQE QKKPAPIKSS SKEQETQPIA  60
   61 AGYYALGIRI PKSPSFHSGL DQLADDELDD QVQDQQQEQQ QTGSRFRFSS VEELKAKFEG 120
  121 RKTPLSPPEA AAGGAAGSGA PTTSSSPSSS STSSNSSASA LSSLSQAASS SLASAAANSS 180
  181 ASSSAATYGG GANSAAAALI ASSPFGSQSS TSSLSLSSNA GMSKNAAGAG SGSGSGTTST 240
  241 GAASGSNSLV STLAQHFSAA TSAAASAAAA AASSASAASS SSASSSSTAT NNAASSSIAA 300
  301 SKSPVSAAAA IKNILNATKS VGTSAAAAAA AAATSSSSSP SSAAAVPSSA ATAVAAVPTT 360
  361 SDVPAEEMRP TVAQNLVGGI SISLGIGQRN GGAAPASSAV MVTPNATMVV TTSSLSIRQN 420
  421 GDILPGHPAG LQPSPQTLQQ LTGSPGRARD RNLFYTPPTA SVAMALPALR ETAASEREEL 480
  481 FIQKIQQCCT LFDFSEPLSD LKFKEVKRAA LHEMVDFLTN QNGVITEVIY PEAINMFAVN 540
  541 LFRTLPPSSN PNGAEFDPEE DEPTLESSWP HLQLVYELFL RFLESPDFQP SMAKRFIDHQ 600
  601 FVLQLLDLFD SEDPRERDFL KTVLHRIYGK FLGLRAFIRK QINNVFYRFI YETEHHNGIA 660
  661 ELLEILGSII NGFALPLKEE HKQFLLKVLL PLHKAKSLSV YHPQLTYCVV QFLEKDPSLS 720
  721 EAVIKSLLKF WPKTHSPKEV MFLNELEELL DVIEPAEFQK VMVPLFRQIA KCVSSPHFQV 780
  781 AERALYYWNN EYIMSLITDN SAVILPIMFP ALNRNSKTHW NKTIHGLIYN ALKLFMEIDQ 840
  841 RLFDECSKNY KQEKQMEREK LSQREELWQQ VESLAKTNPE WTKARRFNDC LPVSDSRALC 900
  901 DQYSENSDSA YDQSEQRARQ PPPPLPPQKQ AHQEPREVRQ ALATLTTLNN Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] FFAS03 1.06 No description for 2j63A was found.
    2 View Details [134..245] deduced N/A No confident structure predictions are available.
    3 View Details [246..350] MSA 2.188991 View MSA. No confident structure predictions are available.
    4 View Details [351..441] deduced N/A No confident structure predictions are available.
    5 View Details [442..951] PSI-BLAST 1000.0 No description for 2nppB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.44

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle