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Protein Overview: CG6126-PA

General Information:
Name(s) found: CG6126-PA / FBpp0082730 [FlyBase]
Description(s) found:
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  • gi|23171448|gb|AAF55286.3| CG6126 [Drosophila melanogaster] [NCBI NR]
  • gi|21355657|ref|NP_650528.1| CG6126 [Drosophila melanogaster] [NCBI NR]
  • gi|15291135|gb|AAK92836.1| GH09241p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6126 (CG6126, FBgn0038407). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12023724..12028802. It has the cytological map location 89B7. Based on sequence similarity, it is predicted to have molecular function</span>: organic cation transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6126-PA translation from_gene[CG6126 CG6126 FBgn0038407] seq_release:3 mol_weight=60873 cds_boundaries:(3R:12,023,951..12,028,573[-]) aa_length:555 transcript_info:[CG6126-RA seq_release:3] gene_info:[gene symbol:CG6126 FBgn0038407 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q961R9) GH09241p (CG6126 protein) [DrosMelano7227.FASTAC.txt]
  • CG6126-PA [Drosophila melanogaster]gi|15291135|gb|AAK92836.1| GH09241p [Drosophila melanogaster]gi|21355657|ref|NP_650528.1| CG6126-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(12023930..12024919,12024982..12025616,12028513..12028555); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,G [fly-100309-contam.fasta]
  • GH09241p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG6126-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(12023930..12024919,12024982..12025616,12028513..12028555); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(12023930..12024919,12024982..12025616,12028513..12028555); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG6126 OS=Drosophila melanogaster GN=CG6126 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(12023930..12024919,12024982..12025616,12028513..12028555); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286,FlyMine:FBpp0082730,modMine:FBpp0082730; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG6126 OS=Drosophila melanogaster GN=CG6126 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3R:complement(join(16202791..16202833,16199260..16199894,16198208..16199197)); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286,FlyMine:FBpp0082730,modMine:FBpp0082730; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(16202791..16202833,16199260..16199894,16198208..16199197)); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286,FlyMine:FBpp0082730,modMine:FBpp0082730; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0082730 type=protein; loc=3R:complement(join(16202791..16202833,16199260..16199894,16198208..16199197)); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286,FlyMine:FBpp0082730,modMine:FBpp0082730; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(16202791..16202833,16199260..16199894,16198208..16199197)); ID=FBpp0082730; name=CG6126-PA; parent=FBgn0038407,FBtr0083278; dbxref=FlyBase:FBpp0082730,FlyBase_Annotation_IDs:CG6126-PA,GB_protein:AAF55286.3,REFSEQ:NP_650528,GB_protein:AAF55286,UniProt/TrEMBL:Q961R9,FlyMine:FBpp0082730,modMine:FBpp0082730; MD5=81622ff58b3c24bc65f85cc48182ae23; length=555; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 555 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    Molecular Function: organic cation transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVDYVLEDL MGKLGEFGKY QFLQFFLQVL SGLTAGMHML SLVTVAAVPE HRCFIEGVDN  60
   61 SSLSVTPWNS SAILAAIPLK PNGELESCLM FDPSSPGTNT TINCERYVYD TTYYKTSRTI 120
  121 DWNFVCDRRW MGAIVQTVFM LGVFTGAVTL GGLADKVGRK TVFCWSALFQ LIIGVGVAFI 180
  181 PEYFSFMVAR YLLGIVGSAG AYICGFVLTM ELVGPTKRTV CGITFQAVFA GGIMLVAGWG 240
  241 ALIPDRQWLQ VIYGLHGCLF LGHWWWLDES PRWLWMQGRA AEAVDIVAKG LRINGSGIPV 300
  301 DKEYYVQKAK QQAAAEEKSS AGLSDLFRTP NLRMKTLNVC LCWFANSLVY YGLSLSAGKL 360
  361 YGNPYLILFI MGLVEFPSYI TIVFVLDRLG RRSITSTLML GGGLCCIVAA YIAQGSTTST 420
  421 AVVMAGKLLI AGSFAVIYNY SAELFPTVVR NSAMGLGSMC ARLSGALTPL ITLLDSFDPK 480
  481 IPAVLFGVVA LISGFWVMFL PETMNQPMPE SIEDGENFGK GDTWFSQCAG RKKRQNSVYP 540
  541 DDPEQMVPLK NIESK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..555] PSI-BLAST 26.221849 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.21476253433572 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.47932844880848 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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