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Protein Overview: Sb-PA, FBpp0310459

General Information:
Name(s) found: FBpp0310459 [FlyBase]
Sb-PA / FBpp0082704 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3R:join(11965569..11965609,11966305..11966904,11967101..11967294,11967387..11967712,11968408..11968837,11969352..11969541,11969617..11969914,11970145..11970294,11970350..11970484); ID=FBpp0310459; name=Sb-PB; parent=FBgn0003319,FBtr0344008; dbxref=FlyBase:FBpp0310459,FlyBase_Annotation_IDs:CG4316-PB; MD5=9256aa6d2c526dbc7b633882df6b355b; length=787; release=r5.56; species=Dmel; [FlyBase]
  • The gene Stubble is referred to in FlyBase by the symbol Dmel\Sb (CG4316, FBgn0003319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11954451..11971006. It has the cytological map location 89B4-89B6. It is reported to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: actin filament bundle formation; cytoskeleton organization. 57 alleles are reported. The phenotypes of these alleles are annotated with: leg; ocellar bristle; macrochaeta; tarsal segment 1; chaeta; ventral thoracic disc; tibia; denticle belt. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 787 amino acids

    Gene Ontology:
    Cellular Component: membrane [NAS]
    plasma membrane [ISS]
    Biological Process: cytoskeleton organization [IMP][NAS]
    proteolysis [IEA][NAS]
    morphogenesis of larval imaginal disc epithelium [NAS]
    actin filament bundle assembly [IMP]
    Molecular Function: serine-type endopeptidase activity [IEA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQPTLIRPR LRHRRSTPAA ATKMCPKRHW LVNNRAAGSR GSGGAAARSR RSLDQIVEVL  60
   61 VALIVVNCLA TAAAALITPP DSLESLGSLG IPSSSASSSE DDDDMSSGFY RIPHRLEGYP 120
  121 QLQQLQRGQN FKISPKPCSF GRVEGTCMFV WECIKSEGKH VGMCVDSFMF GSCCTHNYTD 180
  181 NIVLPQTAFS YTRPTKPLTL RPRPPAAPYK PMISGMTTIE RPHGAGTLVI RPSGPHHQGT 240
  241 LARPHPPPYQ SKPTTASDLH GSASHPSSSS SSSSSSNPNS IWHTSTQQQQ QQQHQQNQQN 300
  301 HWQMTTEPSF ITKPRPTGWT KPGIVNLPMP ARPSKPSKPT KKPIVYDRTP PPPPSVPPST 360
  361 STSTTSTSLI WPAQTHPPQP HRPTRPQLSP GTSLAASSSS HWPSSTTSTT SSTTSTTTTT 420
  421 TTTRRTTTPT TTTRRTTTNK PTRPYQRPTT ATSSSSTSTT SSKTPTTTRP ISSSSSSSSG 480
  481 IVTSSQRPTQ PTHRTPVLAT SGIETNEISD SSIPDAGALG HVKTISAARS ECGVPTLARP 540
  541 ETRIVGGKSA AFGRWPWQVS VRRTSFFGFS STHRCGGALI NENWIATAGH CVDDLLISQI 600
  601 RIRVGEYDFS HVQEQLPYIE RGVAKKVVHP KYSFLTYEYD LALVKLEQPL EFAPHVSPIC 660
  661 LPETDSLLIG MNATVTGWGR LSEGGTLPSV LQEVSVPIVS NDNCKSMFMR AGRQEFIPDI 720
  721 FLCAGYETGG QDSCQGDSGG PLQAKSQDGR FFLAGIISWG IGCAEANLPG VCTRISKFTP 780
  781 WILEHVR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..268] MSA 3.168995 View MSA. No confident structure predictions are available.
    2 View Details [269..416] PSI-BLAST 9.69897 Plasminogen
    3 View Details [417..787] PSI-BLAST 76.154902 No description for 2f83A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • receptor activity
    		•  2.17093251092775 bayes_pls_golite062009
  • binding
    		•  1.90408871052739 bayes_pls_golite062009
  • hydrolase activity
    		•  1.84706864202908 bayes_pls_golite062009
  • peptidase activity
    		•  1.80645788247419 bayes_pls_golite062009
  • signal transducer activity
    		•  1.66079544444023 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.66079544444023 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.56029095187292 bayes_pls_golite062009
  • protein binding
    		•  1.52504676895038 bayes_pls_golite062009
  • endopeptidase activity
    		•  1.33798168430886 bayes_pls_golite062009
  • catalytic activity
    		•  0.280235123429996 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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