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Protein Overview: Atx2-PB

General Information:
Name(s) found: Atx2-PB / FBpp0082555 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Ataxin-2 is referred to in FlyBase by the symbol Dmel\Atx2 (CG5166, FBgn0041188). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11234158..11242999. It has the cytological map location 88F4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: bristle development; compound eye development; oocyte differentiation; regulation of actin filament polymerization; phagocytosis, engulfment. 11 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; ommatidium; head. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1084 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    Biological Process: regulation of actin filament polymerization [IMP]
    phagocytosis, engulfment [IMP]
    oocyte differentiation [IMP]
    bristle development [IMP]
    compound eye development [IMP]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNNSKRKTR PTGGGASGGI SRYNSNDNSL RPTNNKAGAG GGNGGAAVRP SAQGVYNNTF  60
   61 FMHSATALVG SVVEVRLRSG NIYEGVFRTF SGNFDIALEL PACIKSKNLP EEGKVPKHII 120
  121 FPADTVVTIV AKDFDSQYAT AGAFQTDGAI SDKCNGARPD EKELEPWDSG ANGDIDIELD 180
  181 SAANGWDPNE MFRKNENTFG VTSTFDDSLA SYTVPLDKGD SLEFKEAEAK AEKLAAEIEN 240
  241 NPTCRDRLDL ENGDEEALFA AVERPSTEQD QRGDRGDRER NDRDREREER DRDRDRDRGN 300
  301 KPRGAGDFQL RETMSSDRYI TKQTRSITGP QLSHVGMSSQ GSGRDRDTRG DGSMMMQSGG 360
  361 GSGQGGSTQS TAALMLAGGL KGVGPAPSAN ASADSSSKYS GGSMVKRKTV PQGGKVMRNN 420
  421 VPTGGSNVSV SQGGNGNSVG QNKGGYQPSM GMPSQYSYQG NSQIMHGSSQ YRNQSHMGGA 480
  481 NKLNGDSNAN TNKPLPQRQM RQYQGSQSNS SLNYGGEPQS LGKPVHGSHG GHPGQNSNSP 540
  541 PLQTAGPQQQ QQQQQQQQQQ QQQQQPPQQQ QHQNIQPQGQ NTQPARQVRT RDNQMQELRQ 600
  601 FGQDFQLAPS NTSPPQQQQQ QQQQQQQHQV QQQQQRALQQ SASPPQQQQQ QQQQQQHVVL 660
  661 HQVPQTHLHQ AALSQPHYVP QQQPQQAPLP QQQHVPHHMQ QKAQQQQLVE TQHQHVQKQH 720
  721 QSQPQVQQPP PQLLQDPSQQ PLPIYHTMPP PQTSPVVVTS PVLLEQPPPQ PMPVVQQQQT 780
  781 QQLATPKPEV SPAPPSSNTT TPTGIASTPT AGVIASAGSE KTTPAAPTPT SNSATVPTGT 840
  841 AATAGGATGT TPVVKKHVLN PSAKPFTPRG PSTPNPSRPH TPQTPVPMTN IYTTTGGHVP 900
  901 PAANQPIYVM QPQHPFPPQT HPQAGQPPRL RRSNYPPMAA SQMHVSASAA TGQPLITAGP 960
  961 IPQFIQYGHA PHQQQFQSHT YAPMQMRVYP DQPQQLQFMT QTPQSTTPSP GQPHQQFHPP1020
 1021 PQPSPAGGGP QPAFTPPTQA ATYQLMCVHP QSLLANHYFP PPTPQHPQQN QQQYQIVMQQ1080
 1081 HQPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] FFAS03 1.16 Archaeal homoheptameric Sm protein
    2 View Details [110..249] PSI-BLAST 9.39794 No description for 2dnrA was found.
    3 View Details [250..1084] PSI-BLAST 7.154902 No description for 1y0fA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

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