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Protein Overview: Sra-1-PA

General Information:
Name(s) found: Sra-1-PA / FBpp0082541 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene specifically Rac1-associated protein 1 is referred to in FlyBase by the symbol Dmel\Sra-1 (CG4931, FBgn0038320). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11159001..11164103. It has the cytological map location 88F1. It is reported to have molecular function</span>: Rho GTPase binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; regulation of synapse organization; axon guidance; cell projection assembly; cortical actin cytoskeleton organization; phagocytosis, engulfment. 19 alleles are reported. The phenotypes of these alleles are annotated with: commissure; eye; bouton; intersegmental nerve; larval neuromuscular junction; longitudinal connective; microchaeta; ommatidium; synapse; axon. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1291 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    synapse [ISS]
    Biological Process: cortical actin cytoskeleton organization [IMP]
    regulation of cell shape [IMP]
    phagocytosis, engulfment [IMP]
    regulation of synapse organization [IMP]
    cell projection assembly [IMP]
    axon guidance [IMP]
    Molecular Function: Rho GTPase binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEKITLADA LSNVEVLDEL SLPDEQPCIE AQPCSIIYKA NFDTNFEDRN GFVTGIAKYI  60
   61 EEATTHANLN VLLDEGQKHA VMLYTWRCCS RAIPQPKSNE QPNRVEIYEK TVEVLAPEVN 120
  121 KLLNFMYFQR KAIEAFSGEV KRLCHAEKRK DFVSEAYLLT LGKFINMFAV LDELKNMKSS 180
  181 VKNDYSTYRR AAQFLKVMSD SHTLQESQNL SMFLATQNKI RDTVKDTLEK IVGYEDLLSD 240
  241 VVNICVHMFE TKMYLTPEEK HMLVKVMGFG LFLMDSDACN INKLDQKKKI RLDRIDRIFK 300
  301 NLEVVPLFGD MQIAPFNYIK RSKHFDSSKW PLSSSNAISP QADLMVHLPQ IREDHVKYIS 360
  361 ELARYTNEVT TTVKENPSDA ENRITADLAL RGLQLLSEWT SVVTELYSWK LLHPTDHHQN 420
  421 KECPVEAEEY ERATRYNYTS EEKFALIEVI AMIKGLQVLM ARIETVLCEA IRRNIYSELQ 480
  481 DFVQLSLREP LRKAVKNKKD LIRSIIMSVR ETSADWQKGY EPTDDPVAKG KKDPDGGFRI 540
  541 QVPRLNVGPS STQLYMVRTM LESLIADKSG GKRTLRKDID GNCLLQIDTF HKTSFYWSYL 600
  601 LNFSDTLQKC CDLSQLWYRE FYLEMTMGRK VNKCLVRHQH NEECKDLITM EKRIQFPIEM 660
  661 SMPWILTDHI LQTKEPSMME FVLYPLDLYN DSAYYALTVF RKQFLYDEVE AEVNLCFDQF 720
  721 VYKLSEQIFA HYKQLAGSIF LDKRFRLECE VLGFNFQSYP RNNRYETLLK QRHVQLLGRS 780
  781 IDLNKLITQR INANMHKSIE LAISRFEGND ITGIVELEGL LEANRICHKL LSKYLALDNF 840
  841 DGMVKEANHN VLAPYGRITL HVFVELNYDF LVNYCYNAAT NRFIRTKVNL SSSQAIQREK 900
  901 PPQMSHYYLW GSKQLNAAYS TQYGQYTGFV GSPHFHAMCR LLGYQGIAVV MDIILKDIVK 960
  961 PLIQGSLLQF TKTLMIAMPK SCKLPRCEYG SPGVLSYYQA HLTDIVQYPD AKTELFQSFR1020
 1021 EFGNSIIFCL LIEQALSQEE VCDLLHAALF QNIFPRPFCK ENEKPEAKQK RLEAQFANLQ1080
 1081 IVSNVEKIGT AKQAMIAREG DLLTRERLCC GLSIFEVILN RVKSYLDDPV WCGPPPANGI1140
 1141 IHVDECSEFH RLWSALQFVY CIPVRGTEYT IEELFGEGLN WAGCVMIVLL GQQRRFEALD1200
 1201 FCYHILRVQR VDGKDEDVKG IQLKRMVDRI RRFQVLNSQI FSILNKYLKG GDGEGSNVEH1260
 1261 VRCFPPPQHP SVISSSSHYQ DPQKLRQSIN N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] deduced N/A No confident structure predictions are available.
    2 View Details [99..255] MSA 3.037997 View MSA. No confident structure predictions are available.
    3 View Details [256..337] MSA 1.033978 View MSA. No confident structure predictions are available.
    4 View Details [338..544] deduced N/A No confident structure predictions are available.
    5 View Details [545..641] deduced N/A No confident structure predictions are available.
    6 View Details [642..810] deduced N/A No confident structure predictions are available.
    7 View Details [811..911] MSA 1.022922 View MSA. No confident structure predictions are available.
    8 View Details [912..990] MSA 1.022974 View MSA. No confident structure predictions are available.
    9 View Details [991..1036] MSA 1.019992 View MSA. No confident structure predictions are available.
    10 View Details [1037..1136] deduced N/A No confident structure predictions are available.
    11 View Details [1137..1291] MSA 3.026923 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle