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Protein Overview: stumps-PB

General Information:
Name(s) found: stumps-PB / FBpp0082418 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene stumps is referred to in FlyBase by the symbol Dmel\stumps (CG31317, FBgn0020299). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10402941..10433804. It has the cytological map location 88C6-88C9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: tracheal outgrowth, open tracheal system; oogenesis; open tracheal system development; mesoderm development. 27 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; primordium; anatomical structure; portion of tissue; nervous system; germ layer; embryonic nervous system; tracheal system; embryonic/larval tracheal system; embryonic/larval dorsal branch; embryonic pericardial cell; midgut constriction; egg; circulatory system; multi-cell-component structure. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1012 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [NAS][TAS]
    intracellular [TAS]
    Biological Process: morphogenesis of a branching structure [NAS]
    heart development [NAS]
    epithelial cell migration, open tracheal system [TAS]
    primary branching, open tracheal system [TAS]
    mesodermal cell migration [TAS]
    oogenesis [IMP]
    mesoderm migration [NAS]
    mesoderm development [IEP]
    fibroblast growth factor receptor signaling pathway [NAS][TAS]
    tracheal outgrowth, open tracheal system [IMP]
    gastrulation [NAS]
    open tracheal system development [IMP][NAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLKVENIEM ETFCCDNCGN VNNTSGSSAS GFLGSPGYNM DDILIITAKH SERAYLRATF  60
   61 LKNHFDKITK QRGRKPFNFL HIKIDDGPFS EEIAHKYQNT ALQIVILCPA LLALPHSFLM 120
  121 TQLSAIIRVE KVLAILLDVS EEKVKEMHKS ALPSYYKWRR CVVRDNDQVQ ISNILGIATD 180
  181 ILGRALCQRP PCQDSSGGGG GGLSRSFSSC TEGFTVLPKK VKLGQNKVVA LLAEPLEKND 240
  241 TLKLQVEKSG ELIELRNFKC RNPYTLQFNI PEACMEISTM IEIRIEKNNK SLGARPIKCE 300
  301 SRLRELEQLL RIEDSPIEFM CHALGIGPVE RDALDQHLLQ CFQRNMPPNF HLLSGPSERQ 360
  361 PHFFTRLESS PEEYPTLLHF AARWGLNRLC IQLMECPGGD TACGVRNCAG RTPAELAEQE 420
  421 GHHKLAQNIV SFAEFHELTT MYHYFKGVTP PGESCPKPSA NVVIEAHPVK AGKTNKPPKE 480
  481 LPTAEYMEMS SGSERENTPE VRTKTETLAI SNLNYISVET EDENLQASVA EKKVESEKKL 540
  541 PEAGNQPGPE KTTNELRINE PPYYQSKEQN QQPKELKNQS KSLDEVDAAP LYQTDKFSQE 600
  601 CSQLLENQLG NDYVLQPSNV PVAQDDGNYL FQPSNRPVEE PLRLNRCTNR QPGYGTLKRS 660
  661 ASDASAASHT RSNADDELAE IMHDFKNNVL SIRDVEVLVE RWKHRNDVQQ SFREKQDQID 720
  721 QLRREYERIQ EQVKSHLKRE TPFERIKKFF LRSKTPGGND SLLDETKSSI ATSCSFKSAG 780
  781 GVSSSAGAGR PISSLSLQSV SSSSSSSGRL STGSNCSGAS LGDSGTHSDH EDRRFPHCRM 840
  841 MDNYMVPPTP RPVFTPSSTP GDERHQIVFP SPMSSCQRLN TPTSPTGSEH YQMFPSNIPV 900
  901 YGSQPLVGSQ SSNYLNTIME AKEQAETQHY QNQNGVTLQP IKLNERSNII YGKLTKSSSA 960
  961 SGCSSFKPKQ IPVPCPQVGS IEVQAEVYQN VGDVAPEKDS KAEEETPNYM NC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..223] MSA 1.027955 View MSA. No confident structure predictions are available.
    2 View Details [224..470] PSI-BLAST 13.522879 bcl-3
    3 View Details [471..648] PSI-BLAST 9.045757 Transcription factor inhibitor I-kappa-B-beta, IKBB
    4 View Details [649..884] deduced N/A No confident structure predictions are available.
    5 View Details [885..1012] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.96927469603571 bayes_pls_golite062009
  • protein binding
    		•  1.64872738860757 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.66

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle