Protein Overview: CG6188-PA

General Information:
Name(s) found:	CG6188-PA / FBpp0082120 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG6188 (CG6188, FBgn0038074). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8500331..8501806. It has the cytological map location 87C5. Based on sequence similarity, it is predicted to have molecular function</span>: glycine N-methyltransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: methionine metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	289 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	methionine metabolic process [IEA]
Molecular Function:	glycine N-methyltransferase activity [ISS] folic acid binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSADSVFV ARSDGISAEG VRDQYADGKA AKVWEIFIGD KNSRTDNYKN FLIDMLRNKG  60
   61 CKRVLDVACG TGVDSLMLVE EGFEVVSVDA SDKMLKYALK ERWARRNEAA FDKWVIEEAN 120
  121 WLTLYDDIQE HIQDGFDAVI CLGNSFAHLM DGFGDQREHK QAIGNFEKCL KPGGVLLIDH 180
  181 RNYDNILETG ATPAKSIYYN TSHTADIKTS VLFYCGKPAL VSMDYLIAGN KLTSEFRLSY 240
  241 YPHGLKRFQE ILAEIFSAKA KHQLYGDFKE MSQVKNPAFY IHLIEKPQV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
transferase activity	2.926540904444	bayes_pls_golite062009
methyltransferase activity	1.75500643076741	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	1.71409699782588	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.67663666042395	bayes_pls_golite062009
N-methyltransferase activity	1.57269280784007	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
protein methyltransferase activity	1.09292825105169	bayes_pls_golite062009
RNA methyltransferase activity	0.817509452491588	bayes_pls_golite062009
thiopurine S-methyltransferase activity	0.74333485845978	bayes_pls_golite062009
binding	0.383237930789959	bayes_pls_golite062009
rRNA methyltransferase activity	0.230719796976667	bayes_pls_golite062009
histone methyltransferase activity	0.21038834597251	bayes_pls_golite062009
nucleic acid binding	0.103639608104023	bayes_pls_golite062009
DNA binding	0.0844856573974502	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..289]	PSI-BLAST	44.522879	Crystal Structure of Human Glycine N-Methyltransferase

Protein Overview: CG6188-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: