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Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. Catalysis of the transfer of a methyl group to an acceptor molecule. Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: thiopurine S-methyltransferase activity
Acc: GO:0008119
Aspect: Molecular Function
Desc: Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
Synonyms:
  • S-adenosyl-L-methionine:thiopurine S-methyltransferase activity
  • TPMT
  • 6-thiopurine transmethylase activity
  • thiopurine methyltransferase activity
  • mercaptopurine methyltransferase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008119 - thiopurine S-methyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle