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Protein Overview: CG5844-PA

General Information:
Name(s) found: CG5844-PA / FBpp0082063 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5844 (CG5844, FBgn0038049). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8259824..8261365. It has the cytological map location 87B10. Based on sequence similarity, it is predicted to have molecular function</span>: dodecenoyl-CoA delta-isomerase activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 378 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phagocytosis, engulfment [IMP]
    metabolic process [IEA]
    Molecular Function: dodecenoyl-CoA delta-isomerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRKFGGLLA QQVGQQARFT AASRTFSSTK ALHKDPATQE AEAAPPKNIL VEKDKNITLI  60
   61 GINRPQQRNA IDSLTASQLC DAFANFEADD TSPVAVLYGV GGSFCSGFDI LEISTDEKEE 120
  121 ISVDILMRPE GSVGPTRRQI KKPVVCGING YCIANGLELA LMCDLRVMEE SAVLGFFNRR 180
  181 FGVPMLDAGT IRLPAMIGLS RALDLILTGR PVGSQEAHDI GLVNRIVPTG TALGNALELA 240
  241 TCLAKFPQRA LIHDRNSVYS STFETSTFHQ AVQNEVMFTS REIIEDMQNG IKWFNQTFKP 300
  301 DTTHSWLKRD RSMADWDDEE VAEAAAQKEK LKQEQEAALA EAEKQKQAEK AQKRSKKTEE 360
  361 SAAESVDSKD PKDKPNEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..305] PSI-BLAST 75.69897 Enoyl-CoA hydratase (crotonase)
    2 View Details [306..378] MSA 2.014986 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • long-chain-3-hydroxyacyl-CoA dehydrogenase activity
    		•  5.99914207874933 bayes_pls_golite062009
  • long-chain-enoyl-CoA hydratase activity
    		•  5.38361434383109 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  3.92947460544831 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  3.89913842968597 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  3.85567083340773 bayes_pls_golite062009
  • acetyl-CoA C-acyltransferase activity
    		•  3.6090947563188 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  3.4980371783229 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  2.44182589784656 bayes_pls_golite062009
  • dodecenoyl-CoA delta-isomerase activity
    		•  1.80820904754223 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • propionyl-CoA carboxylase activity
    		•  1.20853698666984 bayes_pls_golite062009
  • ligase activity
    		•  0.98581896521131 bayes_pls_golite062009
  • binding
    		•  0.578223105269736 bayes_pls_golite062009
  • 3-hydroxybutyryl-CoA epimerase activity
    		•  0.241955774397835 bayes_pls_golite062009
  • racemase and epimerase activity, acting on hydroxy acids and derivatives
    		•  0.099208209617217 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing C=C bonds
    		•  0.0918189681606029 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle