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View Structure Prediction Details

Protein: CG5844-PA
Organism: Drosophila melanogaster
Length: 378 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5844-PA.

Description E-value Query
Range
Subject
Range
gi|20807045, gi|... - gi|20807045|ref|NP_622216.1| 3-hydroxybutyryl-CoA dehydratase [Thermoanaerobacter tengcongensis MB4]...
gi|20807045 - gi|20807045|ref|NP_622216.1| enoyl-CoA hydratase [Thermoanaerobacter tengcongensis MB4]
301.0 [0..45] [305..2]

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Predicted Domain #1
Region A:
Residues: [1-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRKFGGLLA QQVGQQARFT AASRTFSSTK ALHKDPATQE AEAAPPKNIL VEKDKNITLI  60
   61 GINRPQQRNA IDSLTASQLC DAFANFEADD TSPVAVLYGV GGSFCSGFDI LEISTDEKEE 120
  121 ISVDILMRPE GSVGPTRRQI KKPVVCGING YCIANGLELA LMCDLRVMEE SAVLGFFNRR 180
  181 FGVPMLDAGT IRLPAMIGLS RALDLILTGR PVGSQEAHDI GLVNRIVPTG TALGNALELA 240
  241 TCLAKFPQRA LIHDRNSVYS STFETSTFHQ AVQNEVMFTS REIIEDMQNG IKWFNQTFKP 300
  301 DTTHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.69897
Match: 1dubA
Description: Enoyl-CoA hydratase (crotonase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
long-chain-3-hydroxyacyl-CoA dehydrogenase activity 5.99914207874933 bayes_pls_golite062009
long-chain-enoyl-CoA hydratase activity 5.38361434383109 bayes_pls_golite062009
enoyl-CoA hydratase activity 3.92947460544831 bayes_pls_golite062009
CoA carboxylase activity 3.89913842968597 bayes_pls_golite062009
acetyl-CoA carboxylase activity 3.85567083340773 bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity 3.6090947563188 bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds 3.4980371783229 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 2.44182589784656 bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity 1.80820904754223 bayes_pls_golite062009
catalytic activity 1.46154163027498 bayes_pls_golite062009
propionyl-CoA carboxylase activity 1.20853698666984 bayes_pls_golite062009
ligase activity 0.98581896521131 bayes_pls_golite062009
binding 0.578223105269736 bayes_pls_golite062009
3-hydroxybutyryl-CoA epimerase activity 0.241955774397835 bayes_pls_golite062009
racemase and epimerase activity, acting on hydroxy acids and derivatives 0.099208209617217 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds 0.0918189681606029 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [306-378]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WLKRDRSMAD WDDEEVAEAA AQKEKLKQEQ EAALAEAEKQ KQAEKAQKRS KKTEESAAES  60
   61 VDSKDPKDKP NEK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle