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Protein Overview: Tctp-PA

General Information:
Name(s) found: Tctp-PA / FBpp0081820 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene Translationally controlled tumor protein is referred to in FlyBase by the symbol Dmel\Tctp (CG4800, FBgn0037874). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7035975..7037006. It has the cytological map location 86D8. There is experimental evidence that it has the molecular function</span>: guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell size; positive regulation of multicellular organism growth. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye; 1st posterior cell; wing. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 172 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA][NAS]
    Biological Process: positive regulation of cell size [IMP]
    positive regulation of multicellular organism growth [IMP]
    Molecular Function: guanyl-nucleotide exchange factor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIYKDIITG DEMFADTYKM KLVDDVIYEV YGKLITRQGD DIKLEGANAS AEEADEGTDI  60
   61 TSESGVDVVL NHRLTECFAF GDKKSYTLYL KDYMKKVLAK LEEKSPDQVD IFKTNMNKAM 120
  121 KDILGRFKEL QFFTGESMDC DGMVALVEYR EINGDSVPVL MFFKHGLEEE KC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..172] PSI-BLAST 71.69897 No description for 2hr9A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on sulfur group of donors
    		•  3.4377744251418 bayes_pls_golite062009
  • protein-methionine-R-oxide reductase activity
    		•  3.14392283789517 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor
    		•  2.6167603393936 bayes_pls_golite062009
  • binding
    		•  2.26574571365153 bayes_pls_golite062009
  • transition metal ion binding
    		•  1.89566171684057 bayes_pls_golite062009
  • cation binding
    		•  1.8695053562775 bayes_pls_golite062009
  • metal ion binding
    		•  1.8695053562775 bayes_pls_golite062009
  • ion binding
    		•  1.86234474080078 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.14994807703391 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.009242671721 bayes_pls_golite062009
  • DNA binding
    		•  0.841663070276259 bayes_pls_golite062009
  • catalytic activity
    		•  0.566791077255496 bayes_pls_golite062009
  • protein binding
    		•  0.327945052023132 bayes_pls_golite062009
  • transcription factor activity
    		•  0.202907039530709 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle