YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: mtTFB2-PA

General Information:
Name(s) found: mtTFB2-PA / FBpp0081651 [FlyBase]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • The gene mitochondrial transcription factor B2 is referred to in FlyBase by the symbol Dmel\mtTFB2 (CG3910, FBgn0037778). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5871298..5872987. It has the cytological map location 85F8. Based on sequence similarity, it is predicted to have molecular function</span>: transcription cofactor activity. There is experimental evidence that it is involved in the biological process</span>: transcription from mitochondrial promoter. 6 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; larval brain. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 452 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISS]
    mitochondrion [IDA]
    Biological Process: transcription from mitochondrial promoter [IMP][ISS]
    rRNA methylation [IEA]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: transcription cofactor activity [ISS]
    rRNA (adenine-N6,N6-)-dimethyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPLRCSWSF ARANYSTKKE LVTRYSGDFP EKLLNRKQKV PTHMYIANSE AAARINQYLE  60
   61 PHFQSSGCDT VMELNSGAGY FTRHLLDRES QFRRIILLES MDHFMPKIQE LHTLYPERVK 120
  121 VRQGDFVNLW KLVYMDKMDG GSRVADLLSD VPQKAFTDDI NMLVFGAVGS YPFFKHLINS 180
  181 LIFQTSLFNL GRCEMILAMP PPIYIHLTCN NEIGYLIYRS TSVLFQILFE HKFIAKVPRE 240
  241 DFLPQQMAYS PTKSSKLGKV QSINPEYLYL VKFTPRRNLH ELCQSQDLPA LWFFIKQNYV 300
  301 SRRNRIIPNL EKWVPGCGPR LIINPKSSES VTPIYPDELP KKLPQYSCQS TTMSTRNYYP 360
  361 GINIYTQFGD LLPSQILTLF SQFRQWPEYG ESSFLASLEN ALLKLETAND EPNLEDGVTL 420
  421 PEEDDAEADE IIEEESPVPA TTPVKRRRKA SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..452] PSI-BLAST 48.221849 Crystal structure of human Dimethyladenosine transferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  1.42049721553167 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  1.07629237539972 bayes_pls_golite062009
  • transferase activity
    		•  1.07321114919891 bayes_pls_golite062009
  • binding
    		•  1.06990970478592 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.06467956103007 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.04881630872808 bayes_pls_golite062009
  • DNA binding
    		•  1.03011331296251 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.718731143662013 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.619676326387443 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.527930488619791 bayes_pls_golite062009
  • mitochondrial transcription initiation factor activity
    		•  0.481383105532041 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  0.473668177706488 bayes_pls_golite062009
  • transcription factor binding
    		•  0.149382105526243 bayes_pls_golite062009
  • protein binding
    		•  0.0283208412023089 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle